Christine Gey

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Background There is a steadily increasing demand for producing higher yields of biopharmaceuticals as recombinant proteins, and it is anticipated that this will further expand during the next decades. Among the most frequent proteins produced are growth factors, monoclonal antibodies, hormones and blood coagulation factors. The production of recombinant(More)
OBJECTIVE To determine in fetal sheep the effect of betamethasone on myelination in relation to stage of myelination, number of treatment courses, dose, and route of administration. METHODS Fetal expression of myelin basic protein (MBP), a marker of mature oligodendrocytes and myelin, was determined between 0.27 and 0.93 gestation. Short-term(More)
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