Christine E Bredfeldt

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Spatial frequency tuning in the lateral geniculate nucleus of the thalamus (LGN) and primary visual cortex (V1) differ substantially. LGN responses are largely low-pass in spatial frequency, whereas the majority of V1 neurons have bandpass characteristics. To study this transformation in spatial selectivity, we measured the dynamics of spatial frequency(More)
Neural responses in primary visual cortex (area V1) are selective for the orientation and spatial frequency of luminance-modulated sinusoidal gratings. Selectivity could arise from enhancement of the cell's response by preferred stimuli, suppression by nonoptimal stimuli, or both. Here, we report that the majority of V1 neurons do not only elevate their(More)
It has been shown recently that neurons in V2 respond selectively to the edges of figures defined only by disparity (cyclopean edges). These responses are orientation selective, often preferring similar orientations for cyclopean and luminance contours, suggesting that they may support a cue-invariant representation of contours. Here, we investigate the(More)
BACKGROUND Personal health records (PHRs) are an important tool for empowering patients and stimulating health action. To date, the volitional adoption of publicly available PHRs by consumers has been low. This may be partly due to patient concerns about issues such as data security, accuracy of the clinical information stored in the PHR, and challenges(More)
Previous experiments have shown that V2 neurons respond to complex stimuli such as cyclopean edges (edges defined purely by binocular disparity), angles, and motion borders. It is currently unknown whether these responses are a simple consequence of converging inputs from a prior stage of processing (V1). Alternatively, they may identify edges in a way that(More)
BACKGROUND Studying rare outcomes, new interventions and diverse populations often requires collaborations across multiple health research partners. However, transferring healthcare research data from one institution to another can increase the risk of data privacy and security breaches. METHODS A working group of multi-site research programmers evaluated(More)
BACKGROUND Training is a critical part of health information technology implementations, but little emphasis is placed on post-implementation training to support day-to-day activities. The goal of this study was to evaluate the impact of post-implementation training on key electronic health record activities. METHODS Based on feedback from providers and(More)
BACKGROUND Multi-site health sciences research is becoming more common, as it enables investigation of rare outcomes and diseases and new healthcare innovations. Multi-site research usually involves the transfer of large amounts of research data between collaborators, which increases the potential for accidental disclosures of protected health information(More)
Background: Studying rare outcomes, new interventions and diverse populations often requires collaborations across multiple health research partners. However, transferring healthcare research data from one institution to another can increase the risk of data privacy and security breaches.