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The optimal timing of exogenous surfactant application to reduce pulmonary injury and dysfunction was investigated in a rat lung ischaemia and reperfusion injury model. Lungs were subjected to flush… (More)
BACKGROUND Pre-ischemic surfactant treatment attenuates ischemia/reperfusion (I/R) injury. In this study we investigate whether exogenous surfactant acts by influencing endogenous intra-alveolar and… (More)
BACKGROUND Surfactant inactivation results from ischemia/reperfusion injury and plays a major role in the pathogenesis of primary graft dysfunction after clinical lung transplantation. Thus,… (More)
1 Institute of Anatomy, University of Bern, Baltzerstr. 2, CH-3012 Bern, Switzerland 2 Department of Cardiothoracic and Vascular Surgery, Friedrich Schiller University, Erlanger Allee 101, D-07747… (More)