Four heuristic algorithms based on or inspired by the well-known Tabu Search method have been used to cast heuristically optimized schedules for a clinical training unit of a hospital. It has been found experimentally that the algorithm of choice for this problem depends on the exact goal being sought where the execution time is one of the components of the… (More)
BACKGROUND Although previous research has demonstrated that referral to pre-dialysis clinics is associated with favourable objective outcomes, the benefit of a pre-dialysis clinic from the perspective of patient-perceived subjective outcomes, such as quality of life (QOL), is less well defined. METHODS A retrospective incident cohort study was conducted… (More)
[This corrects the article DOI: 10.1186/s40697-015-0048-7.].
BACKGROUND Agreement between spot and 24-hour urine protein measurements is poor in kidney transplant recipients. We investigated whether using formulae to estimate creatinine excretion rate (eCER), rather than assuming a standard creatinine excretion rate, would improve the estimation of proteinuria from spot urine samples in kidney transplant recipients.… (More)
BACKGROUND The 2012 Kidney Dialysis Initiative Global Outcomes chronic kidney disease (CKD) classification scheme subdivides stage 3 CKD and incorporates the urinary albumin-to-creatinine ratio (ACR). The aim of this study was to evaluate whether the novel scheme provides graded risk in kidney transplant recipients (KTRs). METHODS Prevalent KTRs with… (More)
BACKGROUND Although intravenous saline is the accepted prophylactic measure for the prevention of contrast- induced acute kidney injury, the oral route could offer an equivalent, practical, and cost saving approach. A systematic review of randomized trials that compared oral versus intravenous volume expansion for the prevention of radiocontrast-induced… (More)
BACKGROUND Varenicline is a nicotinic receptor partial agonist indicated for the cessation of smoking. It is regarded as having no or minimal renal toxicity. A single case report has linked it to acute interstitial nephritis. CASE PRESENTATION A 56 year-old female with a long-standing history of idiopathic membranous glomerulonephritis presented on… (More)
The task of scheduling medical staff for evening rounds in the Clinical Teaching Unit of the Ottawa Hospital is a long complicated task due to its complexity. Three main classifications of staff, combined with various rotations, skill sets, clinical teams and vacation periods have combined to create a difficult scheduling problem. As there were no… (More)