Christina Tu Tu

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It has recently been suggested that neuronal cell death in response to many brain insults may be mediated by the upregulation of tumor necrosis factor receptor (TNFR) family members and their ligands. In the present study, we investigated whether the expression of the TNFR family death domain receptor, Fas, and its ligand, FasL, is altered in association(More)
In this video, we demonstrate the preparation of E18 cortical rat neurons. E18 cortical rat neurons are obtained from E18 fetal rat cortex previously dissected and prepared. The E18 cortex is, upon dissection, immediately dissociated into individual neurons. It is possible to store E18 cortex in Hibernate E buffer containing B27 at 4 degrees C for up to a(More)
Data of the Shanghai Tumor Registry were examined for incidence rates of leukemia among children, ages 0-14 years. Between 1972 and 1978, leukemia developed in 344 children; 175 (52%) had acute lymphocytic leukemia. The incidence rates were 4.5 per 100,000 boys and 3.3 per 100,000 girls. The incidence of leukemia peaked between 2 and 7 years of age.
In this video, we demonstrate the technique of soft lithography with polydimethyl siloxane (PDMS) which we use to fabricate a microfluidic device for culturing neurons. Previously, a silicon wafer was patterned with the design for the neuron microfluidic device using SU-8 and photolithography to create a master mold, or what we simply refer to as a(More)
such as cooling and/or delayed fixation can increase MVBs in axons. Indeed, the number and area of MVBs in the axon shaft was significantly increased by such conditions. We conclude that abnormal cargoes and/or manipulations of axons stimulate de-novo formation of MVBs as an artifact or secondary response to dystrophic conditions, abnormal slowing of(More)
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