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  • Xiaorong Zhu, An Zhou, +8 authors Donald Steiner
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences…
  • 2002 (First Publication: 26 July 2002)
  • The subtilisin-like proprotein convertases PC1/3 (SPC3) and PC2 (SPC2) are believed to be the major endoproteolytic processing enzymes of the regulated secretory pathway. They are expressed togetherContinue Reading
  • Xiaorong Zhu, Lelio Orci, Raymond Carroll, Christina Norrbom, Mariella Ravazzola, Donald Steiner
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2002 (First Publication: 22 July 2002)
  • The neuroendocrine processing endoproteases PC2 and PC1/3 are expressed in the β cells of the islets of Langerhans and participate in the processing of proinsulin to insulin and C-peptide. We haveContinue Reading
  • Arunangsu Dey, Gregory M. Lipkind, +5 authors Donald Steiner
  • Medicine, Biology
  • Endocrinology
  • 2005 (First Publication: 1 February 2005)
  • To define the biological significance of the initial cleavage at the proglucagon (PG) interdomain site, K70-R71 downward arrow, we created two interdomain mutants, K70Q-R71Q and R71A. CotransfectionContinue Reading
  • Jens F Rehfeld, Jens René Bundgaard, +4 authors Lennart Friis-Hansen
  • Biology, Medicine
  • Endocrinology
  • 2008 (First Publication: 1 April 2008)
  • Most peptide hormone genes are, in addition to endocrine cells, also expressed in neurons. The peptide hormone cholecystokinin (CCK) is expressed in different molecular forms in cerebral neurons andContinue Reading
  • Jens F Rehfeld, Xiaorong Zhu, +8 authors Lennart Friis-Hansen
  • Chemistry, Medicine
  • The Biochemical journal
  • 2008 (First Publication: 1 October 2008)
  • Cellular synthesis of peptide hormones requires PCs (prohormone convertases) for the endoproteolysis of prohormones. Antral G-cells synthesize the most gastrin and express PC1/3, 2 and 5/6 in the ratContinue Reading
  • Christina Norrbom, Marianne Steding-Jessen, +5 authors Ellen Christine Leth Loekkegaard
  • Medicine
  • American journal of surgery
  • 2019 (First Publication: 1 April 2019)
  • BACKGROUND Adhesive bowel obstruction is associated with considerable morbidity and mortality, but the magnitude of the risk is debated. METHOD In a national cohort of all Danish women with anContinue Reading
  • Klaus F. Kofoed, Christina Norrbom, +10 authors Carsten Sand
  • Medicine
  • Acta dermato-venereologica
  • 2015 (First Publication: 15 January 2015)
  • Risk of human papillomavirus (HPV) transmission during laser vaporisation of genital warts or loop electrode excision procedure is controversial. An oral rinse, a nasal swabs, history of HPV relatedContinue Reading
  • Annette Settnes, Märta FinkTopsoee, +8 authors Helga Margrethe Gimbel
  • Medicine
  • Journal of minimally invasive gynecology
  • 2019 (First Publication: 15 November 2019)
  • STUDY OBJECTIVE To monitor and report nationwide changes in the rates of and complications after different methods for benign hysterectomy, operative hysteroscopy, myomectomy and embolization inContinue Reading