Christina Hederstierna

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CONCLUSION Hormone replacement therapy (HRT) may have a protective effect on hearing impairment in postmenopausal women. New guidelines for classification of audiometric configuration in age-related hearing loss are suggested. OBJECTIVES To describe prevalence of hearing loss and audiometric configuration in a group of middle-aged women with respect to(More)
OBJECTIVE to investigate auditory function in subjects with early Alzheimer's disease, mild cognitive impairment and with subjective memory complaints, in search of signs of central auditory processing dysfunction even in early stages of cognitive impairment. DESIGN AND SUBJECTS a consecutive group of men and women, referred to the Memory Clinic at the(More)
CONCLUSION Young and middle-aged women with Turner syndrome (TS) have a progressive type of hearing impairment, deteriorating rapidly in adult age. The hearing decline seems to consist of two patterns: a mid-frequency dip, likely of a genetic origin, and a high-frequency loss resembling age-related hearing impairment -- possibly influenced by estrogen(More)
OBJECTIVE The state of hearing in 75-year old persons was measured in a population based epidemiological study with the aim of studying if hearing had changed during a time span of 29 years. DESIGN An epidemiological study of generational effects in three age cohorts. STUDY SAMPLE Three age cohorts were included: cohort 1 (n: 267) born in 1976-77,(More)
BACKGROUND Epidemiological studies have shown that women have better high-frequency thresholds than men in virtually all age groups, and that age-related hearing decline starts after 30 in men but not until after the age of 50 in women. This coincides with the menopausal transition in most women, thus leading us to hypothesize that the menopause triggers(More)
Turner syndrome is a chromosomal aberration affecting 1:2000 newborn girls, in which all or part of one X chromosome is absent. This leads to ovarial dysgenesis and little or no endogenous estrogen production. These women have, among many other syndromal features, a high occurrence of ear and hearing problems, and neurocognitive dysfunctions, including(More)
This study was conducted to compare the pattern of age-related hearing decline in individuals with and without self-reported previous occupational noise exposure. This was a prospective, population-based, longitudinal study of individuals aged 70-75 years, from an epidemiological investigation, comprising three age cohorts. In total there were 1013 subjects(More)
BACKGROUND/AIMS Central auditory function can be studied to monitor the progression of mild cognitive impairment to dementia. Our aim was to address this issue in a prospective longitudinal setting. METHODS Tests of central hearing function were performed on 70 subjects with either Alzheimer's disease (AD) or mild cognitive impairment, and in controls(More)
CONCLUSIONS An unexpected rapid hearing decline remained after the 10-year follow up, similar to the hearing decline in 70-year-old women in reference materials. No clear changes concerning hearing in the peri- and postmenopausal period were noted. OBJECTIVE To assess whether hearing decline correlates with menopause and/or cortisol blood levels. (More)