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After publication of this manuscript [1], we became aware that two citations that cover the prokaryotic SPFH1 proteins (here called paraslipins (SPFH1a) and eoslipins (SPFH1b)) [2] and the association of these SPFH1 proteins with NfeD proteins [3] which had been included in earlier versions of the manuscript had erroneously gotten lost during the(More)
The transmembrane protein YuaF from B. subtilis is a member of the NfeD-like clan with a potential role in maintaining membrane integrity during conditions of cellular stress. nfeD-genes are primarily found in highly conserved operon structures together with the gene of another membrane protein belonging to the SPFH superfamily, in this case YuaG. This(More)
BACKGROUND The SPFH protein superfamily is a diverse family of proteins whose eukaryotic members are involved in the scaffolding of detergent-resistant microdomains. Recently the origin of the SPFH proteins has been questioned. Instead, convergent evolution has been proposed. However, an independent, convergent evolution of three large prokaryotic and three(More)
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