Christin Kauert

Learn More
The present study describes short-term modifications of the representation of the fingers at the cortex. Somatosensory evoked potentials were stimulated at the 1st, 3rd and 5th finger, and at the 1st and 5th fingers after anaesthesia of the 2nd, 3rd and 4th fingers. Somatotropic arrangement of the fingers was determined by dipole localization. After local(More)
We investigated immunohistochemically the phenotypes of mononucleated cells invading pancreatic islets of diabetic BB/OK rats in comparison to the diabetes-resistant parental strain, and 12 and 120 days after a temporary treatment (10 days) with a monoclonal antibody (1 mg/kg b.w.) directed against interleukin 2 receptor (IL 2R) combined with a(More)
Despite the existence of circumstantial evidence, a direct proof of an autoimmune basis for beta cell destruction in human type I diabetes has not yet been obtained. The present study was designed to test on Wistar rats whether a low-dose streptozotocin (SZ) treatment in combination with complete Freund's adjuvant (CFA) could be a useful approach to induce(More)
Pancreatic islets obtained from the congenic LEW.1BB/OK rat strain (MHC identical, different in genetic background from BB/OK rats) were grated into diabetic BB/OK rats. The recipients were treated for 10 d with 1.0 mg/kg bw anti-IL2 receptor monoclonal antibody (ART-18) in combination with 1.5 mg/kg bw cyclosporin A, which resulted in indefinite graft(More)
A number of 17.5- to 18.5-day-old fetal pancreases were grafted under the kidney capsule of streptozotocin-diabetic rats. Eight syngeneically grafted glands were sufficient to reverse the diabetes of the recipients within 4 weeks when the recipient rats were treated with insulin for 18 days after transplantation. Eight allogeneic fetal pancreases obtained(More)
Carotid endarterectomy (CEA) reduces the risk of stroke in patients with symptomatic (>50%) and asymptomatic (>60%) carotid artery stenosis. Here we report the midterm results of a microsurgical non-patch technique and compare these findings to those in the literature. From 1998 to 2009 we treated 586 consecutive patients with CEA. CEA was performed, under(More)
Streptozotocin diabetic rats were treated with a syngeneic splenic islet transplantation. 17 weeks later the insulin content and the beta-cell mass were investigated in the host pancreas and compared with untreated diabetic or normal rats. The diabetic animals retained 8% of beta-cells, and 2.5% of insulin content as compared with normal controls.(More)
From 148 BB-rats 76 animals (51.4%) developed hyperglycaemia within 55th to 178th day of life. Already before diagnosis of diabetes a great variety in pancreatic insulin content and morphometrically determined relative beta-cell volume density were visible. Despite of this great heterogeneity two types in the course of beta-cell destruction could be(More)