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Effect of sodium nitroprusside on growth and terpenoid indole alkaloid production in Catharanthus roseus hairy root cultures
Nitric oxide (NO) is known as a signaling molecule involved in elicitor‐induced defense responses of plants. Sodium nitroprusside (SNP), a donor of NO, stimulates catharanthine formation in… Expand
Engineering of genetic control tools in Synechocystis sp. PCC 6803 using rational design techniques.
- S. C. Albers, V. Gallegos, C. A. M. Peebles
- Biology, Medicine
- Journal of biotechnology
- 20 December 2015
Cyanobacteria show promise as photosynthetic microbial factories capable of harnessing sunlight and CO2 to produce valuable end products, but few genetic control tools have been characterized and… Expand
Examining the transcriptional response of overexpressing anthranilate synthase in the hairy roots of an important medicinal plant Catharanthus roseus by RNA-seq
BackgroundClinically important anti-cancer drugs vinblastine and vincristine are solely synthesized by the terpenoid indole alkaloid (TIA) pathway in Catharanthus roseus. Anthranilate synthase (AS)… Expand
Flavonoid glucosides from the hairy roots of Catharanthus roseus.
- Ill-Min Chung, A. Ahmad, +6 authors K. Y. San
- Chemistry, Medicine
- Journal of natural products
- 9 March 2009
Four new flavonoid glucosides, 3',4'-di-O-methylquercetin-7-O-[(4''-->13''')-2''',6''',10''',14'''-tetramethylhexadec-13'''-ol-14'''-enyl]-beta-D-glucopyranoside (1),… Expand
Evaluating Light‐Induced Promoters for the Control of Heterologous Gene Expression in Synechocystis sp. PCC 6803
Cyanobacteria are enticing microbial factories, but little is understood how their gene control elements respond to the periodic availability to light. This research tested the capability of PpsbAII… Expand
Still stable after 11 years: A Catharanthus roseus Hairy root line maintains inducible expression of anthranilate synthase
Hairy root cultures generated using Agrobacterium rhizogenes are an extensively investigated system for the overproduction of various secondary metabolite based pharmaceuticals and chemicals. This… Expand
A comprehensive time-course metabolite profiling of the model cyanobacterium Synechocystis sp. PCC 6803 under diurnal light:dark cycles.
- Allison Werner, C. Broeckling, A. Prasad, C. A. M. Peebles
- Biology, Medicine
- The Plant journal : for cell and molecular…
- 1 July 2019
Cyanobacteria are a model photoautotroph and a chassis for the sustainable production of fuels and chemicals. Knowledge of photoautotrophic metabolism in the natural environment of day/night cycles… Expand
Genetic Engineering of Cyanobacteria: Design, Implementation, and Characterization of Recombinant Synechocystis sp. PCC 6803.
Synechocystis sp. PCC 6803 is a model cyanobacterium which has been investigated to produce a variety of fuels and chemicals. Genetic mutations are of interest for studying photosynthesis and… Expand
New catharanthusopimaranoside A and B from hairy root cultures of Catharanthus roseus
- I. M. Chung, M. Ali, S. C. Chun, K. Y. San, C. A. M. Peebles, A. Ahmad
- Chemistry of Natural Compounds
- 30 October 2008
Two new compounds catharanthusopimaranoside A (1) and catharanthusopimaranoside B (2) along with three known compounds have been isolated from the hairy root cultures of Catharanthus roseus. Their… Expand