Christianna E Purnell

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OBJECTIVE The purpose of this study was to conduct a systematic review of the literature of cardiovascular factors pertaining to incident Alzheimer disease (AD). METHODS A systematic literature review was conducted of all studies of cardiovascular risk factors for incident AD listed in PubMed in English from 2000 to 2007. Risk factors included(More)
Homebound seniors suffer from high levels of functional impairment and are high-cost users of acute medical services. This article describes a 7-year experience in building and sustaining a physician home visit program. The House Calls for Seniors program was established in 1999. The team includes a geriatrician, geriatrics nurse practitioner, and social(More)
OBJECTIVES To describe communication experiences of surrogates who had recently made a major medical decision for a hospitalized older adult. DESIGN Semistructured interviews about a recent hospitalization. SETTING Two hospitals affiliated with one large medical school: an urban public hospital and a university-affiliated tertiary referral hospital. (More)
OBJECTIVE To investigate the association between statin use, incident dementia, and Alzheimer disease (AD) in a prospective elderly African American cohort. DESIGN Two stage design with a screening interview followed by a comprehensive in-home assessment conducted over an eight-year period. Diagnoses of incident AD and dementia were made by consensus.(More)
OBJECTIVE To build a conceptual model of the role of communication in decision making, based on literature from medicine, communication studies and medical ethics. METHODS We proposed a model and described each construct in detail. We review what is known about interpersonal and patient-physician communication, described literature about(More)
OBJECTIVES To examine the frequency of surrogate decisions for in-hospital do-not-resuscitate (DNR) orders and the timing of DNR order entry for surrogate decisions. DESIGN Retrospective cohort study. SETTING Large, urban, public hospital. PARTICIPANTS Hospitalized adults aged 65 and older over a 3-year period (1/1/2004-12/31/2006) with a DNR order(More)
BACKGROUND There is little information on the association of the APOEe4 allele and AD risk in African populations. In previous analyses from the Indianapolis-Ibadan dementia project, we have reported that APOE ε4 increased the risk for Alzheimer's disease (AD) in African Americans but not in Yoruba. This study represents a replication of this earlier work(More)
OBJECTIVES Patients with serious mental illness are living longer. Yet, there remain few studies that focus on healthcare utilization and its relationship with comorbidities in these elderly mentally ill patients. DESIGN Comparative study. Information on demographics, comorbidities, and healthcare utilization was taken from an electronic medical record(More)
OBJECTIVES The population of older patients with schizophrenia is increasing. This study describes health outcomes, utilization, and costs over 10 years in a sample of older patients with schizophrenia compared with older patients without schizophrenia. METHODS An observational cohort study of 31,588 older adults (mean age: 70.44 years) receiving care(More)
INTRODUCTION High blood glucose levels may be responsible for the increased risk for dementia in diabetic patients. METHODS A secondary data analysis merging electronic medical records (EMRs) with data collected from the Indianapolis-Ibadan Dementia project (IIDP). Of the enrolled 4105 African Americans, 3778 were identified in the EMR. Study endpoints(More)