Christiane Marchiani

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In recent years there has been considerable interest in the prognostic value of general parameters of cell-mediated immunity in cancer patients. Hence immune modulation and immunopharmacology are becoming an increasingly important area of cancer therapy. A very simple clinical assay for possible immunostimulating agents is to look for skin test conversion(More)
C 1821 is a purified glycoprotein extract of Klebsiella pneumoniae serotype 2 with immunomodulating properties in animals (in vivo and in vitro) and in humans (in vitro). The compound is devoid of any apparent toxicity when given orally. The aim of the present work was to evaluate the effects of a short term oral administration of C 1821 on delayed(More)
The activity of RU 41740, a glycoprotein extract from Klebsiella pneumoniae has been investigated on some polymorphonuclear (PMN) functions. Chemotaxis, random migration and oxidative metabolism (assessed by chemiluminescence, O2 consumption and O2- generation) were studied in parallel. PMN were collected from adult and aged human volunteers. Experiments(More)
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