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- Angela Marzocchetti, Christian Wuthrich, +5 authors Igor J. Koralnik
- Journal of NeuroVirology
- 2008

The polyomavirus JC (JCV) is the etiologic agent of progressive multifocal leukoencephalopathy (PML). JCV remains quiescent in kidneys, where it displays a stable archetypal regulatory region (RR). Conversely, rearranged JCV RR, including tandem repeat patterns found in the central nervous system (CNS) of PML patients, have been associated with… (More)

- C. Wuthrich
- 1994

The rapid development of scanning and measuring hardware for medical imaging and for scientiic experiments, the introduction of animation techniques into common use have created the need to understand n-dimensional raster geometry, where n > 3. After a brief review of continuous geometry in R n , this paper presents the discrete regular structure called a… (More)

- Michael N Khoury, David C Alsop, +7 authors Igor J Koralnik
- Annals of neurology
- 2014

OBJECTIVE
To determine the frequency of hyperintense cortical signal (HCS) on T1-weighted precontrast magnetic resonance (MR) images in progressive multifocal leukoencephalopathy (PML) patients, its association with seizure risk and immune reconstitution inflammatory syndrome (IRIS), and its pathologic correlate.
METHODS
We reviewed clinical data… (More)

- Shruti P Agnihotri, Christian Wuthrich, +7 authors Igor J Koralnik
- Annals of neurology
- 2014

JC virus (JCV) is the etiologic agent of progressive multifocal leukoencephalopathy, JCV granule cell neuronopathy, and JCV encephalopathy. Whether JCV can also cause meningitis has not yet been demonstrated. We report a case of aseptic meningitis resulting in symptomatic hydrocephalus in a human immunodeficiency virus-seronegative patient. Brain imaging… (More)

- C Rappe, M Nygren, G Lindstrom, H R Buser, O Blaser, C Wuthrich
- Environmental science & technology
- 1987

7053-7065. (41) Howard, J. A.; Scaiano, J. C. Landolt Bornstein New Series, Kinetic Rate Constants of Radical Reactions in Solution: Part d , Oxyl-, Peroxyl-, and Related Radicals; SpringerVerlag: Berlin-Heidelberg, 1984; Series II/13d. (42) Paris, D. F.; Wolfe, N. L.; Steen, W. C.; Baughman, G. L. Appl. Enuiron. Microbiol. 1983, 45(3), 1153-1155. (43)… (More)

- William Stein, Christian Wuthrich
- Math. Comput.
- 2013

We explain how to use results from Iwasawa theory to obtain information about p-parts of Tate-Shafarevich groups of specific elliptic curves over Q. Our method provides a practical way to compute #X(E/Q)(p) in many cases when traditional p-descent methods are completely impractical and also in situations where results of Kolyvagin do not apply, e.g., when… (More)

We explain how to combine deep results from Iwasawa theory with explicit computation to obtain information about p-parts of Tate-Shafarevich groups of elliptic curves over Q. This method provides a practical way to compute #X(E/Q)(p) in many cases when traditional p-descent methods are completely impractical and also in situations where results of Kolyvagin… (More)

- Hayden Schwenk, Lynn Ramirez-Avila, +7 authors Asim Ahmed
- The Pediatric infectious disease journal
- 2014

Progressive multifocal leukoencephalopathy is a rare, demyelinating disease of the central nervous system caused by JC virus. Fewer than 30 cases have been reported in HIV- and non-infected children. We report the case of a 15-year-old girl with progressive multifocal leukoencephalopathy and AIDS who presented with nystagmus, dysarthria and ataxia.… (More)

Let E/Q be an elliptic curve and p be a prime number, and let G be the Galois group of the extension of Q obtained by adjoining the coordinates of the p-torsion points on E. We determine all cases when the Galois cohomology group H ( G,E[p] ) does not vanish, and investigate the analogous question for E[p] when i > 1. We include an application to the… (More)