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  • Christian Riehle, Adam R. Wende, +14 authors E. Dale Abel
  • Biology, Medicine
  • Molecular and Cellular Biology
  • 2014 (First Publication: 7 July 2014)
  • ABSTRACT Insulin and insulin-like growth factor 1 (IGF-1) receptor signaling pathways differentially modulate cardiac growth under resting conditions and following exercise training. These effectsExpand
  • Adam R. Wende, Brian T. O'Neill, +18 authors E. Dale Abel
  • Medicine, Biology
  • Molecular and Cellular Biology
  • 2014 (First Publication: 22 December 2014)
  • ABSTRACT Sustained Akt activation induces cardiac hypertrophy (LVH), which may lead to heart failure. This study tested the hypothesis that Akt activation contributes to mitochondrial dysfunction inExpand
  • J. David Symons, Shawna L McMillin, +11 authors E. Dale Abel
  • Biology, Medicine
  • Circulation research
  • 2009 (First Publication: 8 May 2009)
  • Impaired insulin signaling via phosphatidylinositol 3-kinase/Akt to endothelial nitric oxide synthase (eNOS) in the vasculature has been postulated to lead to arterial dysfunction and hypertension inExpand