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PURPOSE Volumetric measurements of neonatal brain tissues may be used as a biomarker for later neurodevelopmental outcome. We propose an automatic method for probabilistic brain segmentation in neonatal MRIs. MATERIALS AND METHODS In an IRB-approved study axial T1- and T2-weighted MR images were acquired at term-equivalent age for a preterm cohort of 108(More)
A number of algorithms for brain segmentation in preterm born infants have been published, but a reliable comparison of their performance is lacking. The NeoBrainS12 study (http://neobrains12.isi.uu.nl), providing three different image sets of preterm born infants, was set up to provide such a comparison. These sets are (i) axial scans acquired at 40 weeks(More)
This paper discusses a module-based vision for designing BDI-based multi-agent programming languages. The introduced concept of module is generic and facilitates the implementation of different agent concepts such as roles and agent profiles, or to adopt common programming techniques such as encapsulation and information hiding. This vision is applied to(More)
OBJECTIVES To determine the influence of iterative reconstruction (IR) on quantitative computed tomography (CT) measurements of emphysema, air trapping, and airway wall and lumen dimensions, compared to filtered back-projection (FBP). METHODS Inspiratory and expiratory chest CTs of 75 patients (37 male, 38 female; mean age 64.0 ± 5.7 years) were(More)
Despite much research on companion robots and affective virtual characters, a comprehensive discussion on a generic architecture is lacking. We compile a list of possible requirements of a companion robot and propose a generic architecture based on this list. We explain this architecture to uncover issues that merit discussion. The architecture can be used(More)
OBJECTIVE To determine the agreement and reliability of fully automated coronary artery calcium (CAC) scoring in a lung cancer screening population. MATERIALS AND METHODS 1793 low-dose chest CT scans were analyzed (non-contrast-enhanced, non-gated). To establish the reference standard for CAC, first automated calcium scoring was performed using a(More)
RATIONALE AND OBJECTIVES Radiology practice has become increasingly based on volumetric images (VIs), but tests in medical education still mainly involve two-dimensional (2D) images. We created a novel, digital, VI test and hypothesized that scores on this test would better reflect radiological anatomy skills than scores on a traditional 2D image test. To(More)
OBJECTIVES To determine the variation in quantitative computed tomography (CT) measures of air trapping in low-dose chest CTs of heavy smokers. METHODS We analysed 45 subjects from a lung cancer screening trial, examined by CT twice within 3 months. Inspiratory and expiratory low-dose CT was obtained using breath hold instructions. CT air trapping was(More)
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