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  • Rafaela Holtappels, Natascha K. A. Grzimek, Christian O. Simon, Doris Thomas, Doris Dreis, Matthias J Reddehase
  • Biology, Medicine
  • Journal of virology
  • 2002 (First Published: 15 June 2002)
  • CD8 T cells are the principal effector cells in the resolution of acute murine cytomegalovirus (mCMV) infection in host organs. This undoubted antiviral and protective in vivo function of CD8 T cellsContinue Reading
  • Vanessa Wilhelmi, Christian O. Simon, +9 authors Natascha K. A. Grzimek
  • Biology, Medicine
  • Journal of virology
  • 2008 (First Published: 15 October 2008)
  • Despite its high coding capacity, murine CMV (mCMV) does not encode functional enzymes for nucleotide biosynthesis. It thus depends on cellular enzymes, such as ribonucleotide reductase (RNR) andContinue Reading
  • Verena Boehm, Christian O. Simon, +7 authors Matthias J Reddehase
  • Biology, Medicine
  • Journal of virology
  • 2008 (First Published: 1 December 2008)
  • Cytomegaloviruses express glycoproteins that interfere with antigen presentation to CD8 T cells. Although the molecular modes of action of these "immunoevasins" differ between cytomegalovirusContinue Reading
  • Torsten Däubner, Annette Fink, +12 authors Niels A W Lemmermann
  • Biology, Medicine
  • The Journal of general virology
  • 2010 (First Published: 1 June 2010)
  • Gene m164 of murine cytomegalovirus belongs to the large group of 'private' genes that show no homology to those of other cytomegalovirus species and are thought to represent 'host adaptation' genesContinue Reading