Christian Kukla

Learn More
BACKGROUND AND PURPOSE Systemic thrombolysis is the only therapy proven to be effective for ischemic stroke. Telemedicine may help to extend its use. However, concerns remain whether management and safety of tissue plasminogen activator (tPA) administration after telemedical consultation are equivalent in less experienced hospitals compared with tPA(More)
BACKGROUND AND PURPOSE Systemic thrombolysis represents the only proven therapy for acute ischemic stroke, but safe treatment is reported only in established stroke units. One major goal of the ongoing Telemedic Pilot Project for Integrative Stroke Care (TEMPiS) in Bavaria is to extend the use of tissue plasminogen activator (tPA) treatment in nonurban(More)
BACKGROUND Arterial hypertension is a major risk factor for cardiovascular damage. The results of several studies suggest that target organ damage is greater in hypertensive persons with high blood pressure variability. METHODS AND RESULTS During 3.3 years of follow-up, we studied the relationship between circadian blood pressure changes and the(More)
BACKGROUND IV thrombolysis represents the most effective acute stroke therapy. However, it is almost exclusively performed in stroke centers and is not available in most community areas. The Telemedical Pilot Project for Integrative Stroke Care (TEMPiS) was started in February 2003. Twelve community hospitals with no or very limited stroke thrombolysis(More)
BACKGROUND AND PURPOSE Contrast transcranial Doppler ultrasonography is a new method to detect intracardiac right-to-left shunts, such as the patent foramen ovale. However, the methodology of the procedure varies considerably among investigators. This study was undertaken to assess the influence of methodological parameters on the results of the contrast(More)
BACKGROUND The occurrence of lacunar infarction is closely related to arterial hypertension. However, there is only limited and partly controversial knowledge regarding the possible pathogenetic role of circadian blood pressure changes. OBJECTIVE To evaluate the relationship between circadian blood pressure rhythm, occurrence, and extent of lacunar(More)
Cell cycle characteristics including labeling indices (LI), duration of S-phase (Ts), and total cell cycle time (Tc) were determined in 54 standard-risk, newly diagnosed patients with acute myeloid leukemia following an infusion of bromodeoxyuridine. Remission induction therapy consisting of cytosine arabinoside and daunomycin was then administered to all(More)
  • Joamin Gonzalez-Gutierrez, Ivica Duretek, +5 authors Hugo F. Lopez
  • 2016
The viscosity of feedstock materials is directly related to its processability during injection molding; therefore, being able to predict the viscosity of feedstock materials based on the individual properties of their components can greatly facilitate the formulation of these materials to tailor properties to improve their processability. Many empirical(More)
  • 1