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Magnetic particle imaging (MPI) is a novel imaging method that was first proposed by Gleich and Weizenecker in 2005. Applying static and dynamic magnetic fields, MPI exploits the unique characteristics of superparamagnetic iron oxide nanoparticles (SPIONs). The SPIONs' response allows a three-dimensional visualization of their distribution in space with a(More)
In magnetic particle imaging (MPI), the spatial distribution of magnetic nanoparticles is determined by applying various static and dynamic magnetic fields. Due to the complex physical behavior of the nanoparticles, it is challenging to determine the MPI system matrix in practice. Since the first publication on MPI in 2005, different methods that rely on(More)
Magnetic Particle Imaging (MPI) is an emerging technology in the field of (pre)clinical imaging. The acquisition of a particle signal is realized along specific sampling trajectories covering a defined field of view (FOV). In a system matrix (SM) based reconstruction procedure, the commonly used acquisition path in MPI is a Lissajous trajectory. Such a(More)
The magnetic particle imaging (MPI) technology is a new imaging technique featuring an excellent possibility to detect iron oxide based nanoparticle accumulations in vivo. The excitation of the particles and in turn the signal generation in MPI are achieved by using oscillating magnetic fields. In order to realize a spatial encoding, a field-free point(More)
Kurzfassung. In der Computertomographie können metallische Objek-te oder Bewegungen durch Patienten zu Inkonsistenzen innerhalb der Projektionswerte führen. Bei der anschließenden Rekonstruktion der to-mographischen Schnittbilder kommt es durch diese inkonsistenten Daten zu Artefakten, welche die diagnostische Aussagekraft des Bildes beein-flussen können.(More)
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