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- Erwan Bézard, Sandrine Ferry, +5 authors Pierre Sokoloff
- Nature Medicine
- 2003
In monkeys rendered parkinsonian with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), expression of the dopamine D3 receptor was decreased. However, levodopa-induced dyskinesia (LID), similar to… (More)
- Pierre Sokoloff, Jorge Pablo DÃaz, +4 authors Christian Gross
- CNS & neurological disorders drug targets
- 2006
The role of the D(3) receptor has remained largely elusive before the development of selective research tools, such as selective radioligands, antibodies, various highly specific pharmacological… (More)
- Sylvia Navailles, Bernard Bioulac, Christian Gross, Philippe De Deurwaerdère
- Neurobiology of Disease
- 2010
Benefit and motor side effects of l-DOPA in Parkinson's disease have been related to dopamine transmission in the striatum. However, the putative involvement of serotonergic neurons in the… (More)
- Sylvia Navailles, Bernard Bioulac, Christian Gross, Philippe De Deurwaerdère
- Neurobiology of Disease
- 2011
The therapeutic benefit of L-DOPA is commonly attributed to restoration of dopamine (DA) extracellular levels in the striatum of Parkinsonian patients. However, the loss of efficacy of L-DOPA after… (More)
- Alim Louis Benabid, Pierre Pollak, +6 authors Jacqueline Perret
- Stereotactic and functional neurosurgery
- 1994
In animal models of Parkinson's disease (PD), it is postulated that the excessive output from the subthalamic nucleus (STN) plays a critical role. Selective lesions or high frequency electrical… (More)
- Pierre Pollak, A. L. Benabid, +6 authors Jacqueline Perret
- Revue neurologique
- 1993
In Parkinson's disease, experimental studies favour a neuronal hyperactivity of the subthalamic nucleus. We carried out a subthalamic nucleus electrical stimulation in a patient aged 51, suffering… (More)
- Patrick Strube, Stephan W. Tohtz, Eike Karl Hoff, Christian Gross, Carsten Perka, Michael Putzier
- European Spine Journal
- 2010
Progression of superior adjacent segment degeneration (PASD) could possibly be avoided by dynamic stabilization of an initially degenerated adjacent segment (AS). The current study evaluates ex vivo… (More)
- Michael Putzier, Julia Franziska Funk, +5 authors Frank M Kandziora
- European Spine Journal
- 2005
A retrospective clinical–radiological study to evaluate the long-term outcome after artificial disc replacement was performed. The objective is to investigate long-term results after implantation of… (More)
- Vincent Dousset, Bruno Brochet, +6 authors J. M. Caillé
- AJNR. American journal of neuroradiology
- 1995
PURPOSE
To study bystander demyelination in multiple sclerosis with an experimental in vivo model of toxic demyelination.
METHODS
Toxic demyelinating lesions were created in two monkeys by… (More)
- Olivier Guillin, Nathalie Griffon, +4 authors Pierre Sokoloff
- European journal of pharmacology
- 2003
Brain-derived neurotrophic factor (BDNF) belongs to a family of proteins related to nerve growth factor, which are responsible for neuron proliferation, survival and differentiation. A more diverse… (More)