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  • Christian G. Brilla, Guihua Zhou, Luis Shiguero Matsubara, Karl T. Weber
  • Chemistry, Medicine
  • Journal of molecular and cellular cardiology
  • 1994 (First Publication: 1 July 1994)
  • Myocardial fibrosis is associated with an activated renin-angiotensin-aldosterone system (RAAS). In renovascular hypertension, this presents as a reactive perivascular and interstitial fibrosis inContinue Reading
  • Christian G. Brilla, Luis Shiguero Matsubara, Karl T. Weber
  • Medicine
  • Journal of molecular and cellular cardiology
  • 1993 (First Publication: 1 May 1993)
  • In arterial hypertension associated with primary or secondary hyperaldosteronism myocardial fibrosis is an important determinant of pathologic hypertrophy. To further examine the relationship betweenContinue Reading
  • Christian G. Brilla, Joseph S Janicki, Karl T. Weber
  • Medicine
  • Circulation research
  • 1991 (First Publication: 1 July 1991)
  • Left ventricular hypertrophy (LVH) in rats with genetic hypertension is accompanied by abnormal myocardial diastolic stiffness and impaired coronary reserve. Whether these functional defects areContinue Reading