Christian Ellinger

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This study analyzed the longitudinal cephalometric head films of 37 edentulous patients over a 10-year period. The purpose of the investigation was to document changes within the craniofacial complex, residual ridge resorption, and position of the dentures. The changes were correlated with the following variables: age, sex, skeletal pattern, number of years(More)
Rats were exposed to nitrate (NO3-) in drinking water, to phenylmercuryacetate (PMA) by gavage and to NO3- and PMA together during 4 different experiments. PMA impaired kidneys, NO3- thyroid gland, and NO3- and PMA together both organs. In the last case a synergistic effect on the thyroid gland was shown. The lowest effective concentration of NO3- was 40(More)
The pesticide dichlorvos inhibits not only cholinesterase but also alkaline phosphatase, lactate dehydrogenase and glutamate dehydrogenase competitively. A mixed type inhibition of glutamic-oxaloacetic transaminase is in contrast to the increased activity of glutamic-pyruvic transaminase after dichlorvos application. The activity of leucine aminopeptidase(More)
The adoptive transfer of tumor-antigen specific CD8+ T lymphocytes has shown highly promising but somewhat limited benefit in tumor immunotherapy. The poor objective clinical efficacy observed in early studies has been overcome partly by integration of patient preconditioning and improved technologies for T cell receptor gene therapy. Nevertheless, in(More)
In recent years, activation of the patient’s immune system to defend against tumors was demonstrated to be a promising alternative strategy to classical cancer treatments. Dendritic cells (DCs) can present antigens on MHC-II and -I leading to the activation of CD4 or CD8 T cells, respectively. Stimulated CD4 T cells act as helper cells for cytotoxic CD8 T(More)
Depending on the mechanisms by which cancer develops and the strategies tumors use to escape the immune system, cancer therapies are more or less successful. A combination of different therapeutic agents, such as dendritic cell (DC) vaccines loaded with tumor antigens and adoptive transfer of tumor-specific T-cells, may enhance the chances of effective(More)