Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer.
- J. Bernier, Christian Domenge, M. van Glabbeke
- MedicineNew England Journal of Medicine
- 6 May 2004
Postoperative concurrent administration of high-dose cisplatin with radiotherapy is more efficacious than radiotherapy alone in patients with locally advanced head and neck cancer and does not cause an undue number of late complications.
Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data. MACH-NC Collaborative Group. Meta analysis of chemotherapy on…
- J. Pignon, Bourhis Jh, Christian Domenge, L. Designé
- Medicine
- 1 April 2001
Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data
- J. Pignon, J. Bourhis, Christian Domenge, L. Designé, O. B. O. C. C. Group
- MedicineThe Lancet
- 18 March 2000
Percutaneous gastrostomy with fluoroscopic guidance: single-center experience in 500 consecutive cancer patients.
- T. de Baère, R. Chapot, A. Roche
- MedicineRadiology
- 1 March 1999
Fluoroscopically guided gastrostomy is highly feasible and safe and provides adequate feeding support, even when percutaneous endoscopic gastrostome is impossible, and long-term minor complications mainly involved the disturbances and nearly always resolved once the tube was exchanged.
Full-dose reirradiation for unresectable head and neck carcinoma: experience at the Gustave-Roussy Institute in a series of 169 patients.
- R. de Crevoisier, J. Bourhis, F. Eschwège
- MedicineJournal of Clinical Oncology
- 1 November 1998
Full-dose reirradiation combined with chemotherapy was feasible in patients with inoperable HNC, and the incidence and severity of late toxicity was markedly increased in comparison to that observed after the first irradiation.
[Electrochemotherapy, a new antitumor treatment: first clinical trial].
- L. Mir, M. Belehradek, C. Paoletti
- MedicineComptes rendus de l'Academie des sciences. Serie…
- 1991
The first clinical trial of ECT, applied to patients with permeation nodules of head and neck squamous carcinomas, was well tolerated by patients, no serious incident occurred and a clear antitumor efficiency was found.
Antitumor electrochemotherapy: New advances in the clinical protocol
- Christian Domenge, S. Orlowski, L. Mir
- MedicineCancer
- 1 March 1996
Variations of ECT protocol were tested on patients with head and neck squamous cell carcinoma with HNSCC permeation nodules to determine how to improve it.
Electrochemotherapy, a new antitumor treatment. First clinical phase I‐II trial
- M. Belehradek, Christian Domenge, B. Luboinski, S. Orlowski, J. Belehradek, L. Mir
- MedicineCancer
- 15 December 1993
The authors report the first Phase I‐II trial of electrochemotherapy, a new antitumor treatment consisting of electrical pulses administered to the tumor several minutes after intravenous injection of bleomycin, observed on subcutaneously transplanted tumors and on spontaneously occurring mammary carcinomas.
Randomized trial of neoadjuvant chemotherapy in oropharyngeal carcinoma
- Christian Domenge, C. Hill, B. Luboinski
- MedicineBritish Journal of Cancer
- 1 December 2000
Overall survival was significantly better in the neoadjuvant chemotherapy group than in the control group, with a median survival of 5.1 years versus 3.3 years in the no chemotherapy group.
Early locoregional high-dose radiotherapy is associated with long-term disease control in localized primary angiocentric lymphoma of the nose and nasopharynx
It is confirmed that chemotherapy gives a low complete remission rate in localized nasal NK/T cell lymphoma, and first-line radiotherapy seems to give favorable results, whereas its results are poorer when administered after resistance to chemotherapy.
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