Christian Colin

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This paper presents the point of view of a designer about declarative modelers. We propose a model of this point of view. Our approach is based on the work we have done to develop some of our declarative modelers. It takes into account the main functions used by a designer in these modelers. We explain also the scene-building process and we present working(More)
Diffuse infiltrating gliomas are the most common tumors of the central nervous system (CNS), naturally progressing from a lower-grade to a higher-grade malignancy. Several genetic alterations have been correlated with astrocytic tumors; however, a number of as yet unknown genes may also be involved. Therefore, we set out to search for genes that are(More)
The ADAMs comprises a family of cell surface proteins with putative roles in cell-cell and/or cell-matrix interactions and in protease activities. In this work, we have examined the expression level and the methylation status of the 5' upstream region of the adhesion molecule ADAM23 in two brain tumor cell lines (A172 and T98G) as well as in three primary(More)
One of the objectives in image synthesis is to create 2D-images. However, the properties of images are not usually used in the modelling process. This paper describes a work that takes into account the characteristics of images from the beginning of the design process. 3D-scenes are automatically created so that their visualisation respects the properties(More)
BACKGROUND The CHD7 (Chromodomain Helicase DNA binding protein 7) gene encodes a member of the chromodomain family of ATP-dependent chromatin remodeling enzymes. Mutations in the CHD7 gene are found in individuals with CHARGE, a syndrome characterized by multiple birth malformations in several tissues. CHD7 was identified as a binding partner of PBAF(More)
  • Christian Colin, Emmanuel Desmontils, Jean-Yves Martin, Jean-Philippe Mounier
  • 2009
This paper presents the point of view of a designer about declarative modelers. First, we propose a model of this point of view. Our approach is based on the work we have done to develop some of our declarative modelers. It takes into account the main functions used by a designer in these modelers. Then, we explain also the scene-building process and we(More)
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