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  • Vincenzo Cerullo, Michael P. Seiler, +5 authors Brendan Lee
  • Biology, Medicine
  • Molecular therapy : the journal of the American…
  • 2007 (First Publication: 1 February 2007)
  • A major obstacle to the clinical application of systemic adenoviral gene replacement therapy is the host innate immune response. Although recent studies have attempted to characterize the cellularContinue Reading
  • Vincenzo Cerullo, Michael P. Seiler, +5 authors Brendan Lee
  • Biology, Medicine
  • Molecular therapy : the journal of the American…
  • 2007 (First Publication: 1 December 2007)
  • Bioengineering of the factor VIII (FVIII) molecule has led to the production of variants that overcome poor secretion and/or rapid inactivation. We tested six modified FVIII variants for in vivoContinue Reading