Amphipathic homopolymers for siRNA delivery: probing impact of bifunctional polymer composition on transfection.
- Christian Buerkli, Soo Hyeon Lee, Elena V. Moroz, M. Stuparu, J. Leroux, Anzar Khan
- Biology, ChemistryBiomacromolecules
- 22 April 2014
The present system did not rely on the "proton sponge" effect for siRNA delivery, and the transfection efficiency of polymer/siRNA complexes remained unchanged in the presence of bafilomycin A1, a proton pump inhibitor.