Christian Brem

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The formation of brain edema and subsequent intracranial hypertension are major predictors of unfavorable outcome following traumatic brain injury (TBI). Previously, we reported that arginine vasopressin (AVP) receptor antagonists reduce post-traumatic and post-ischemic brain edema in mice. The aim of the current study was to investigate further the(More)
Basilar artery (BA) perforator aneurysms may lead to severe subarachnoid hemorrhage (SAH). The acute management is uncertain. The anatomic approach is challenging both for coiling and clipping, and flow diverter stenting may be dangerous due to the required antiplatelet therapy. We report on our experiences in eight patients. We retrospectively analyzed(More)
The current gold standard in the assessment of lateral intracranial dural arteriovenous fistulas (LDAVF) is digital subtraction angiography (DSA). However, magnetic resonance imaging (MRI) is a non-invasive emerging tool for the evaluation of such lesions. The aim of our study was to compare the DSA to our 3 T MR-imaging protocol including a highly spatial(More)
Softwareentwicklung auf der Basis der Objektorientiertung (OO) hat in fast allen Bereichen der Softwaresysteme wesentliche Bedeutung erlangt. Die Tätigkeit des System-Funktionstests wird dadurch naturgemäß tangiert, wiewohl eine detaillierte Überprüfung der Fragestellung klarlegt, daß die überwiegende Menge an bisherigen "Best-Practices" für das Testen(More)
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