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An adjustable computerized atlas of the human brain has been developed, which can be adapted to fit individual anatomy. It is primarily intended for positron emission tomography (PET) but may also be used for single photon emission CT, transmission CT, magnetic resonance imaging, and neuroimaging-based procedures, such as stereotactic surgery and(More)
We measured regional cerebral blood flow (rCBF) with positron emission tomography to study changes in anatomical structures during the course of learning a complicated finger sequence of voluntary movements. Motor learning was accompanied by rCBF increases in the cerebellum, decreases in all limbic and paralimbic structures, and striatal decreases which(More)
The computerized brain atlas programme (CBA) provides a powerful tool for the anatomical analysis of functional images obtained with positron emission tomography (PET). With a repertoire of simple transformations, the data base of the CBA is first adapted to the anatomy of the subject's brain represented as a set of magnetic resonance (MR) or computed(More)
We report on the observation of two neutrino-induced events which have an estimated deposited energy in the IceCube detector of 1.04±0.16 and 1.14±0.17 PeV, respectively, the highest neutrino energies observed so far. These events are consistent with fully contained particle showers induced by neutral-current ν(e,μ,τ) (ν(e,μ,τ)) or charged-current ν(e)(More)
We present the results of time-integrated searches for astrophysical neutrino sources in both the northern and southern skies. Data were collected using the partially-completed IceCube detector in the 40-string configuration recorded maximum likelihood ratio method is used to search for astrophysical signals. The data sample contains 36,900 events: 14,121(More)
This report describes a strategy for measurement of regional CBF that rigorously accounts for differing tracer partition coefficients and recirculation, and is convenient for use with positron emission tomography. Based on the Kety model, the measured tissue concentration can be expressed in terms of the arterial concentration, the rate constant K, and the(More)
A contour-finding algorithm is described by which the object periphery is outlined in positron emission tomography (PET) scans. The positions of maximum slopes are determined in the projections. These positions are shown to correspond well to the borders of the activity region. By backprojecting these points in the projections into the image plane, the size(More)
CBA, a software tool used to improve quantification and evaluation of neuroimaging data has been developed. It uses a detailed 3-dimensional brain atlas that can be adapted to fit the brain of an individual patient represented by a series of displayed images. Anatomical information from the atlas can then be introduced into the images. If the patient has(More)
3 Abstract The first sensors of the IceCube neutrino observatory were deployed at the South Pole during the austral summer of 2004-05 and have been producing data since February 2005. One string of 60 sensors buried in the ice and a surface array of 8 ice Cherenkov tanks took data until December 2005 when deployment of the next set of strings and tanks(More)
A computerized brain atlas adjustable to the patient's anatomy would serve serveral purposes. It could be used in stereotaxic surgery. Even more important would be its use in medical imaging to identify various brain structures, such as the basal ganglia and their nuclei, as well as individual cortical gyri. This atlas could be used for additional mapping(More)