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Genetically tractable model plants offer the possibility of defining the plant O(3) response at the molecular level. To this end, we have isolated a collection of ozone (O(3))-sensitive mutants of Arabidopsis thaliana. Mutant phenotypes and genetics were characterized. Additionally, parameters associated with O(3) sensitivity were analysed, including(More)
A knowledge–based tutorial computer system in rheumatology had been integrated in a standard course of internal medicine for students in their fourth year of medical curriculum. The tutoring software is based on the expert–system shell–toolkit D3 and its tutorial component D3Trainer. Based on the knowledge base " Rheuma", which is also used for consultation(More)
Problembasiertes Lernen erfordert eine möglichst große Anzahl von Fallstudien. Jedoch ist die Erstellung von Trainingsfällen ein aufwändiger Prozess. Die Kerninformation ist in Fallbeschreibungen, z.B. Arztbriefen in der Medizin, bereits enthalten. Um daraus Trainingsfälle generieren zu können, ist eine Nachbearbeitung und semantische Annotierung(More)
The new media such as the internet and digital imaging offer new opportunities in medical education. In addition to conventional lectures, we developed a case-based simulation training program of 17 hematology cases using the novel training system d3web.Train. We evaluated the assessment of this internet course by medical students, as well as their results(More)
Objective: We introduce a case-based training program using the novel system d3web.Train. It allows fast development of case studies for a computer course using available clinical patient records. We evaluated the training program during a rheumatology course for medical students. Methods: Students received a short introduction into the system (d3web.Train)(More)
In [BBH + 04] we presented an approach for generating diagnostic training cases from dismissal reports in order to reduce both author's effort and time-to-class for new training cases. In the past year we finished the tool CaseImporter and several authors used it to implement their own training systems, some of them being part of lectures. In this paper, we(More)
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has become a powerful and widespread analytical tool in all fields of life science. Compared with other techniques, its high accuracy and sensitivity makes it a superior method, especially for the analysis of nucleic acids. Recent problems in the analysis of nucleic(More)
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