Christian A. Keller

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Central aspects in the pathogenesis of scrub typhus, an infection caused by Orientia (O.) tsutsugamushi, have remained obscure. Its organ and cellular tropism are poorly understood. The purpose of this study was to analyze the kinetics of bacterial dissemination and associated inflammatory responses in infected tissues in an experimental scrub typhus mouse(More)
T cells are known to contribute to immune protection against scrub typhus, a potentially fatal infection caused by the obligate intracellular bacterium Orientia (O.) tsutsugamushi. However, the contribution of CD8+ T cells to protection and pathogenesis during O. tsutsugamushi infection is still unknown. Using our recently developed BALB/c mouse model that(More)
Etiology of severe non-malaria febrile illness in northern Tanzania: a prospective cohort study. et al. Universal single-probe RT-PCR assay for diagnosis of dengue virus infections. Cryptic properties of a cluster of dominant flavivirus cross-reactive antigenic sites. To the Editor: Relapsing fevers are paroxysmal bloodstream infections caused by(More)
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