Christa Caspers

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A series of novel arylpiperazines bearing a pyrrolidin-2-one fragment were synthesized and evaluated for their binding affinity for a 1-and a 2-adrenoceptors (ARs) as well as their antiarrhythmic and antihypertensive activities. The highest affinity for the a 1-AR was displayed by
A series of novel arylpiperazines bearing a pyrrolidin-2-one fragment were synthesized and evaluated for their binding affinity for alpha1- and alpha2-adrenoceptors (ARs) as well as their antiarrhythmic and antihypertensive activities. The highest affinity for the alpha1-AR was displayed by 1-{3-[4-(2-chloro-phenyl)-piperazin-1-yl]-propyl}-pyrrolidin-2-one(More)
28 Minireview – Role of endothelin-1 receptor blockers on hemodynamic parameters and oxidative stress. 35 9-Methyl->-carboline has restorative effects in an animal model of Parkinson’s disease. 54 Effects of blockade of central dopamine D and D receptors on thermoregulation, metabolic rate and running performance. 62 Effects of 2-chloroadenosine on cortical(More)
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