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SUMMARY Life sciences research is based on individuals, often with diverse skills, assembled into research groups. These groups use their specialist expertise to address scientific problems. The in silico experiments undertaken by these research groups can be represented as workflows involving the coordinated use of analysis programs and information(More)
Understanding the logical meaning of any description logic or similar formalism is difficult for most people, and OWL-DL is no exception. This paper presents the most common difficulties encountered by newcomers to the language, that have been observed during the course of more than a dozen workshops , tutorials and modules about OWL-DL and it's predecessor(More)
The reasoning tasks that can be performed with semantic web service descriptions depend on the quality of the domain ontologies used to create these descriptions. However, building such domain ontologies is a time consuming and difficult task.We describe an automatic extraction method that learns domain ontologies for web service descriptions from textual(More)
Semantic Web Services offer the possibility of highly flexible web service architectures, where new services can be quickly discovered, orchestrated and composed into workflows. Most existing work has, however , focused on complex service descriptions for automated composition. In this paper, we describe the requirements from the bioinformatics domain which(More)
The growing quantity and distribution of bioinformatics resources means that finding and utilizing them requires a great deal of expert knowledge, especially as many resources need to be tied together into a workflow to accomplish a useful goal. We want to formally capture at least some of this knowledge within a virtual workbench and middle-ware framework(More)
(my)Grid supports in silico experiments in the life sciences, enabling the design and enactment of workflows as well as providing components to assist service discovery, data and metadata management. The (my)Grid ontology is one component in a larger semantic discovery framework for the identification of the highly distributed and heterogeneous(More)
my Grid is an e-Science research project developing open source high-level middleware to support in silico experiments in biology. In silico experiments use databases and computational analysis rather than laboratory investigations to test hypothesis. This paper provides an overview of services the my Grid project is developing, and the architecture in(More)