Chris Winder

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Four populations of putative serotonergic cells could be detected in the chicken retina by histofluorescence and immunohistochemistry. Numerous (10,000/mm2) small (6 micron diameter) bipolar cells were located towards the middle of the inner nuclear layer, as were sparser (1000/mm2) larger (12 micron diameter) amacrine cells. Very sparse large (greater than(More)
Lead remains a significant occupational health and public health problem. Excessive lead exposure, not only to men exposed at work, but also from lead based paint in older housing and from soil, still persists in the community. From the perspective of human reproduction, lead is known to cause a number of adverse outcomes in both men and women. Reported(More)
We present a concept for developing cooperative characters (agents) for computer games that combines coaching by a human with evolutionary learning. The basic idea is to use prototypical situation-action pairs and the nearest-neighbor rule as agent architecture and to let the human coach provide key situations and his/her wishes for an associated action for(More)
The benefits of using occupational health and safety management systems (OHS MS) have been typically restricted to large scale, multi-site organisations, often from the manufacturing sector. Transferring these benefits to smaller businesses has been fraught with difficulty, with the mechanics and bureaucracy of the system itself sometimes becoming(More)
Ventilatory and carotid body responses to hypoxia have been related to the endogenous release of dopamine by use of the antagonist drug haloperidol. The published studies have produced conflicting data for ventilation. However, antagonist drugs can act at multiple anatomical sites, on multiple pharmacological receptors, often at different dosages, and have(More)
The pathological changes found in the central nervous system of lead-exposed humans and laboratory animals are reviewed. Data in man relate to relatively high exposure levels. In human childhood lead encephalopathy, which occurs with blood lead levels in the range 100-800 micrograms Pb/100 ml, oedema, vacuolation, haemorrhage and reactive glial changes(More)