Chris Scorer

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This study is based on observations made on boys at birth, during infancy, and throughout early childhood. Its purpose was to find out how often the testes were in the scrotum at birth and what happened in later years to those that were not. An analysis of the position of the testes was made in over 3,500 infant boys at birth. Those in whom one or both(More)
1. The aim of the present study was to examine the effects of chronic infusion of the long-acting agonist salmeterol on pulmonary beta(2)-adrenoceptor function in Sprague-Dawley rats in vivo and to elucidate the molecular basis of any altered state. 2. Systemic administration of rats with salmeterol for 7 days compromised the ability of salmeterol and(More)
Descent of the testicle from the abdomen into the scrotum is known to occur at about the eighth month of foetal life. If the transition has not taken place at birth it may do so shortly after. It is said that movement can take place at any time up to puberty but very rarely afterwards. Mothers, midwives and doctors are all aware that the scrotum of the(More)
The aim of the present study was to develop a chronic in vivo model of pulmonary beta(2)-adrenoceptor desensitization and to elucidate the nature and molecular basis of this state. Subcutaneous infusion of rats with albuterol for 7 days compromised the ability of albuterol, given acutely, to protect against acetylcholine-induced bronchoconstriction. The(More)