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Fragmentation of carbonyl oxides by N-oxides: an improved approach to alkene ozonolysis.
[Structure: see text] Ozonolysis of alkenes in the presence of amine N-oxides results in the direct formation of aldehydes. This reaction, which appears to involve an unprecedented trapping andExpand
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'Reductive ozonolysis' via a new fragmentation of carbonyl oxides
Abstract This account describes the development of methodologies for ‘reductive’ ozonolysis, the direct ozonolytic conversion of alkenes into carbonyl groups without the intermediacy ofExpand
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Asymmetric Synthesis of 1,2-dioxanes: Approaches to the Peroxyplakoric Acids.
The stereospecific intramolecular alkylation of a hydroperoxyacetal provides the basis for the first asymmetric synthesis of the dioxane propionate core of the peroxyplakorates. ChemoselectiveExpand
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Rational design of a rapid fluorescent approach for detection of inorganic fluoride in MeCN–H2O: a new fluorescence switch based on N-aryl-1,8-naphthalimide
A fluoride chemosensor (FCS-1) based on 1,8-naphthalimide bearing a trimethylsilyl ether has been designed and synthesized. FCS-1 displayed high selectivity and sensitivity to fluoride in inorganicExpand
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Electrophilic Etherification of α-Heteroaryl Carbanions with Monoperoxyacetals as a Route to Ketene O,O- and N,O-Acetals.
Alkyl ketene acetals are useful reactants in a variety of synthetic processes, and yet, there are limited routes to their formation as isolable products. We now report the successful synthesis andExpand
Biomimetic composites by surface-initiated polymerization of cyclic lactones at anorganic bone: preparation and in vitro evaluation of osteoblast and osteoclast competence.
Biomimetic composites were constructed using anorganic bone to initiate the polymerization of cyclic lactones. The resulting anorganic bone/polylactone composites preserve the inorganic structure andExpand
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Efficient synthesis and conformational investigations of cis-pentacenediols
Diisobutylaluminum hydride is utilized to reduce pentacene-6,13-diones to the corresponding diols, useful precursors to functionalized pentacenes. This pathway is mild and efficient, and produces theExpand
1,1-Dihydroperoxides
Gem-dihydroperoxides (g-DHPs), often referred to as 1,1-dihydroperoxides, are a class of molecules of interest because of their reactivity as well as their utility as synthetic reagents andExpand
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