Chris Rylander

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A major barrier for progress in regenerative medicine is the inability to observe the process of tissue regeneration non-destructively, in real time, and with cellular level resolution. In order to overcome this difficult challenge, we have proposed and developed an imaging-bioreactor system based on fiber micro-devices. Our system is based on directly(More)
BACKGROUND AND OBJECTIVE The subcellular structure of biological cells effects spatial variation of local index of refraction. Differential interference contrast (DIC) microscopy provides a qualitative measure of thin specimen phase retardation and refractive index. A novel imaging device, a differential phase optical low-coherence reflectometer (OLCR),(More)
The hydraulic resistance characterization manuscript chronicles the early development of the hollow-core fiberoptic microneedle device (FMD). The study determined that for straight tubing with an inner bore of 150 μm and a length greater than 50 mm long, Poiseuille’s Law was shown to be accurate within 12% of experimental data for the pressure range of(More)
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