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Experiments designed to examine the energy requirements of neurophysiological function were performed on isolated rabbit retina. Function was altered by photic stimulation or by function-specific drugs, and the response of energy metabolism was assessed by simultaneous measurements of O2 consumption and lactate production. In other experiments, the supply(More)
Modern commercial organisations are facing pressures which have caused them to lose personnel. When they lose people, they also lose their knowledge. Organisations also have to cope with the internationalisation of business forcing collaboration and knowledge sharing across time and distance. Knowledge management (KM) claims to tackle these issues. This(More)
Knowledge Management (KM) is a field that has attracted much attention both in academic and practitioner circles. Most KM projects appear to be primarily concerned with knowledge that can be quantified and can be captured, codified and stored-an approach more deserving of the label Information Management. Recently there has been recognition that some(More)
Subthalamic nucleus deep brain stimulation (STN DBS) ameliorates motor symptoms of Parkinson's disease, but the precise mechanism is still unknown. Here, using a large animal (pig) model of human STN DBS neurosurgery, we utilized fast-scan cyclic voltammetry in combination with a carbon-fiber microelectrode (CFM) implanted into the striatum to monitor(More)
Introduction: The strategies that people use to browse Websites are difficult to analyse and understand: quantitative data can lack information about what a user actually intends to do, while qualitative data tends to be localised and is impractical to gather for large samples. Method: This paper describes a novel approach that combines data from direct(More)
Purpose – This main aim of this article is to explore the relationship between knowledge management (KM) and communities of practice (CoPs) in general and virtual CoPs in particular. A subsidiary aim is to provide some practical guidelines about how virtual CoPs can be facilitated and maintained. Design/methodology/approach – The relationship between KM and(More)
Innovation and knowledge sharing across professional boundaries: Political interplay between boundary objects and brokers. Abstract The article examines the process of innovation and knowledge sharing from a perspective that focuses on the influence that local circumstances can have. In particular, it looks at the problems of knowledge sharing between(More)