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Rearrangements of MLL (encoding lysine-specific methyltransferase 2A and officially known as KMT2A; herein referred to as MLL to denote the gene associated with mixed-lineage leukemia) generate MLL fusion proteins that bind DNA and drive leukemogenic gene expression. This gene expression program is dependent on the disruptor of telomeric silencing 1-like(More)
Crime Analysts (IACA) is committed to a continuing process of professionalization through standards and knowledge development. In 2011, the IACA chartered the SMT Committee for the purpose of defining " analytical methodologies, technologies, and core concepts relevant to the profession of crime analysis. " 1 This document represents the first in a series(More)
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