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A comparison of results of empirical studies of supplementary search techniques and recommendations in review methodology handbooks: a methodological review
Comparison of current practice in using supplementary search methods with methodological guidance shows reasonable consistency between recommended best practice (handbooks) and current practice (methodological studies) as it relates to the application of supplementarySearch methods. Expand
Thromboelastography (TEG) and rotational thromboelastometry (ROTEM) for trauma induced coagulopathy in adult trauma patients with bleeding.
The objective was to determine the diagnostic accuracy of thromboelastography and rotational thrombaelastometry for TIC in adult trauma patients with bleeding, using a reference standard of prothrombin time ratio and/or the international normalized ratio. Expand
A systematic review and economic evaluation of diagnostic strategies for Lynch syndrome.
Results suggest that reflex testing for LS in newly diagnosed CRC patients aged < 50 years is cost- effective, and such testing may also be cost-effective in newly Diagnosing and managing LS, although studies from other countries generally found some strategies to becost-effective compared with no testing. Expand
Staffing in maternity units. Getting the right people in the right place at the right time
Citing this paper Please note that where the full-text provided on King's Research Portal is the Author Accepted Manuscript or Post-Print version this may differ from the final Published version. IfExpand
Immunosuppressive therapy for kidney transplantation in adults: a systematic review and economic model.
A new discrete time-state transition economic model (semi-Markov) was developed, with acute rejection, graft function (GRF) and new-onset diabetes mellitus used to extrapolate graft survival. Expand
The role of systematic reviews of qualitative evidence in evaluating interventions: a case study.
There are a number of ways in which systematic reviews of qualitative evidence can be utilised in conjunction with evidence on intervention effectiveness, without compromising the rigour of the review process, including the use of theory to inform frameworks for synthesis. Expand
Defining the process to literature searching in systematic reviews: a literature review of guidance and supporting studies
If a shared model of the literature searching process can be detected across systematic review guidance documents and, if so, how this process is reported in the guidance and supported by published studies is determined. Expand
Patient-centred care in general dental practice - a systematic review of the literature
A systematic review of the literature reveals a lack of understanding of PCC within dentistry, and in particular general dental practice, and a poor evidence base to support the current patient reported outcome measures as indicators of patient-centredness. Expand
A model-based assessment of the cost–utility of strategies to identify Lynch syndrome in early-onset colorectal cancer patients
Reflex testing for Lynch syndrome in early-onset colorectal cancer patients is predicted to be a cost-effective use of limited financial resources in England and Wales and the effect of prophylactic H-BSO on health-related quality of life (HRQoL) is uncertain and could outweigh the health benefits of testing, resulting in overall QALY loss. Expand
Cost-effectiveness of cetuximab, cetuximab plus irinotecan, and panitumumab for third and further lines of treatment for KRAS wild-type patients with metastatic colorectal cancer.
All three treatments are highly unlikely to be considered cost-effective in this patient population in the United Kingdom and always remain poor value for money. Expand