Chris Barber

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OBJECTIVES To evaluate the clinicoradiologic findings and outcomes of management of simple intratesticular cysts, by review of an 11-year experience. METHODS From March 1994 to September 2005, 24 men underwent scrotal ultrasound scan and follow-up for simple intratesticular cysts. The median follow-up was 32 months (range, 6 to 124 months). The records(More)
BACKGROUND Since the mid-1990s, outbreaks of asthma and extrinsic allergic alveolitis (EAA) have been identified in workers exposed to metalworking fluids (MWFs). The cause of these outbreaks remains to be determined. AIMS To identify and review all previously published occupational lung disease case definitions and diagnostic criteria that have been(More)
A first analysis of a database of shared preclinical safety data for 1214 small molecule drugs and drug candidates extracted from 3970 reports donated by thirteen pharmaceutical companies for the eTOX project (www.etoxproject.eu) is presented. Species, duration of exposure and administration route data were analysed to assess if large enough subsets of(More)
Prostate cancer is at present the most common malignancy in men in the Western world. When localized to the prostate, this disease can be treated by curative therapy such as surgery and radiotherapy. However, a substantial number of patients experience a recurrence, resulting in spreading of tumor cells to other parts of the body. In this advanced stage of(More)
Field and laboratory evidence show natural degradation of toluene, ethylbenzene, m-, pand o-xylenes, 1,3,5-trimethylbenzeneand naphthalene in sulphate reducing groundwater conditions of the Bassendean Sands in the Perth basin, Western Australia. Natural degradation rates were obtained from a groundwater tracer test with deuterated organic compounds injected(More)
In the Arabidopsis root, patterning of the epidermal cell types is position-dependent. The epidermal cell pattern arises early during root development, and can be visualized using reporter genes driven by the GLABRA (GL)2 promoter as markers. The GL2 gene is preferentially expressed in the differentiating hairless cells (atrichoblasts) during a period in(More)
BACKGROUND The use of proteolytic enzymes to improve the cleaning efficacy of washing powders was introduced in the mid 1960s. Many microbial enzymes are known to be potent respiratory sensitizers but previously there has been only one case of occupational asthma associated with workplace exposure in a healthcare worker. AIMS To report two cases of(More)
INTRODUCTION Potential demographic risk factors for outbreaks of respiratory disease due to water-based metalworking fluids (MWFs) were investigated through systematic review of published outbreak investigations. METHODS Search terms were selected by a multidisciplinary team, assisted by an experienced library information service. Several computerized(More)
Bullying is very much an aspect of contemporary society and perhaps it always has been. Many may have experienced it from early childhood while at school, either as victims or perpetrators. The healthcare industry is, sadly, not immune from this phenomenon. This short article seeks to answer the question: 'Is bullying deliberately used as a management tool(More)
Prostate cancer is a leading cause of death among men in Western countries. Whereas the survival rate approaches 100% for patients with localized cancer, the results of treatment in patients with metastasized prostate cancer at diagnosis are much less successful. The patients are usually presented with a variety of treatment options, but therapeutic(More)