Choon-Sheen Lai

Publications15
h-index9
Citations285
Highly Influential Citations13
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An analytical method with a single extraction procedure and two separate high performance liquid chromatographic systems for the determination of artesunate, dihydroartemisinin and mefloquine in…
The combination of two sensitive, selective and reproducible reversed phase liquid chromatographic (RP-HPLC) methods was developed for the determination of artesunate (AS), its active metabolite… Expand
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Chemical constituents and in vitro anticancer activity of Typhonium flagelliforme (Araceae).
AIM OF THE STUDY Typhonium flagelliforme is an indigenous plant of Malaysia and is used by the local communities to treat cancer. This study aims to identify the chemical constituents of Typhonium… Expand
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Typhonium flagelliforme inhibits cancer cell growth in vitro and induces apoptosis: an evaluation by the bioactivity guided approach.
AIM OF THE STUDY Typhonium flagelliforme (Lodd.) Blume (Araceae) is a Malaysian plant used locally to combat cancer. In order to evaluate its antiproliferative activity in vitro and to possibly… Expand
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Validation of high performance liquid chromatography-electrochemical detection methods with simultaneous extraction procedure for the determination of artesunate, dihydroartemisinin, amodiaquine and…
With the expanded use of the combination of artesunate (AS) and amodiaquine (AQ) for the treatment of falciparum malaria and the abundance of products on the market, comes the need for rapid and… Expand
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A simple HPLC-DAD method for the detection and quantification of psychotropic mitragynine in Mitragyna speciosa (ketum) and its products for the application in forensic investigation.
Mitragyna speciosa, a native plant of Thailand and Malaysia known as 'ketum', is a plant of considerable interest. It exhibits strong antinociceptive effect and yet, acts like a psychostimulant. Due… Expand
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Anti-Tumor Action, Clinical Biochemistry Profile and Phytochemical Constituents of a Pharmacologically Active Fraction of S. crispus in NMU-Induced Rat Mammary Tumour Model
Cancer patients seek alternative remedies such as traditional medicinal plants for safe and effective treatment and help overcome the side effects of conventional therapy. Current knowledge indicates… Expand
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Antioxidant, anti-cholinesterase and antibacterial activities of the bark extracts of Garcinia hombroniana
This study reports an antioxidant, anti-cholinesterase, antibacterial activities and total flavonoids content of different extracts (water, methanol, ethyl acetate, dichloromethane andn-hexane) of… Expand
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Cholinesterase inhibitory activity and chemical constituents of Stenochlaena palustris fronds at two different stages of maturity.
Stenochlaena palustris fronds are popular as a vegetable in Southeast Asia. The objectives of this study were to evaluate the anticholinesterase properties and phytochemical profiles of the young and… Expand
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A Comparative Study of the Volatile Constituents of Southeast Asian Coffea arabica, Coffea liberica and Coffea robusta Green Beans and their Antioxidant Activities
Abstract A comparative study on the volatile constituents of green beans of three commercially grown coffees in Southeast Asia, namely Coffea arabica, Coffea robusta and Coffea liberica, and their… Expand
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Polyphenols rich fraction of Dicranopteris linearis promotes fibroblast cell migration and proliferation in vitro.
ETHNOPHARMACOLOGICAL RELEVANCE Dicranopteris linearis is a fern used traditionally for the treatment of skin afflictions such as external wounds, boils and ulcers. However, there are no scientific… Expand
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