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Increased understanding of the molecular basis of colorectal cancer and recognition that extracellular DNA circulates in the plasma and serum of cancer patients enables new approaches to detection and monitoring. We used a polymerase chain reaction (PCR) assay to demonstrate mutant K-ras DNA in the plasma or serum of patients with colorectal cancer. Plasma(More)
Members of the Ras superfamily of small GTP-binding proteins, gamma-subunits of heterotrimeric G proteins and nuclear lamin B are subject to a series of post-translational modifications that produce prenylcysteine methylester groups at their carboxyl termini. The thioether-linked polyisoprenoid substituent can be either farnesyl (C15) or geranylgeranyl(More)
The performance analysis of a differential phase shift keyed (DPSK) communications system, operating in a Rayleigh fading environment, employing convolutional coding and diversity processing is presented. The receiver is the conventional square-law DPSK receiver using soft-decision convolutional decoding. The computationally efficient union bound technique(More)
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