Chooi Yeng Lee

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The emergence of obesity as a pandemic has led to increased efforts to determine the causes for this disorder and potential new treatments to prevent and/or treat those affected by it. The mechanisms underlying the ontogeny of obesity are complex. They involve an interaction between a genetic predisposition to this disorder and environmental conditions that(More)
Glioblastoma multiforme (GBM) may be one of the most challenging brain tumors to treat, as patients generally do not live more than 2 years. This review aimed to give a timely review of potential future treatments for GBM by looking at the latest strategies, involving mainly the use of temozolomide (TMZ). Although these studies were carried out either in(More)
Temozolomide (TMZ) is one of the most effective chemotherapeutic agents for glioblastoma multiforme, but the required high administration dose is accompanied by side effects. To overcome this problem and to further improve TMZ's efficacy, targeted delivery of TMZ by using polymeric nanoparticles has been explored. We synthesised the PLGA-PEG-FOL copolymer(More)
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