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Structural insights into the interaction of the ribosomal P stalk protein P2 with a type II ribosome-inactivating protein ricin

• Xiaojiao Fan, Yuwei Zhu, Chongyuan Wang, Liwen Niu, Maikun Teng, Xin Li
• Scientific reports
• 2016

Ricin is a type II ribosome-inactivating protein (RIP) that depurinates A4324 at the sarcin-ricin loop of 28 S ribosomal RNA (rRNA), thus inactivating the ribosome by preventing elongation factors… (More)

Crystal structure of triple-BRCT-domain of ECT2 and insights into the binding characteristics to CYK-4.

• Yang Zou, Zhenhua Shao, +8 authors Qingguo Gong
• FEBS letters
• 2014

Homo sapiens ECT2 is a cell cycle regulator that plays critical roles in cytokinesis. ECT2 activity is restrained during interphase via intra-molecular interactions that involve its N-terminal… (More)

Structural insights into the recognition of phosphorylated FUNDC1 by LC3B in mitophagy

• Mengqi Lv, Chongyuan Wang, +5 authors Yajun Tang
• Protein & Cell
• 2016

Mitophagy is an essential intracellular process that eliminates dysfunctional mitochondria and maintains cellular homeostasis. Mitophagy is regulated by the post-translational modification of… (More)

Structural determinants for the strict monomethylation activity by trypanosoma brucei protein arginine methyltransferase 7.

• Chongyuan Wang, Yuwei Zhu, +12 authors Yunyu Shi
• Structure
• 2014

Trypanosoma brucei protein arginine methyltransferase 7 (TbPRMT7) exclusively generates monomethylarginine (MMA), which directs biological consequences distinct from that of symmetric… (More)

Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin.

• Debiao Zhao, Xuejuan Wang, +11 authors Qingguo Gong
• Journal of structural biology
• 2014

c-Cbl-associated protein (CAP) is an important cytoskeletal adaptor protein involved in the regulation of adhesion turnover. The interaction between CAP and vinculin is critical for the recruitment… (More)

Crystal structure of the two-subunit tRNA m1A58 methyltransferase TRM6-TRM61 from Saccharomyces cerevisiae

• Mingxing Wang, Yuwei Zhu, +7 authors Xin Li
• Scientific reports
• 2016

The N(1) methylation of adenine at position 58 (m(1)A58) of tRNA is an important post-transcriptional modification, which is vital for maintaining the stability of the initiator methionine… (More)

Cryo-EM structures of fungal and metazoan mitochondrial calcium uniporters

• Rozbeh Baradaran, Chongyuan Wang, Andrew Francis Siliciano, Stephen Barstow Long
• Nature
• 2018

The mitochondrial calcium uniporter (MCU) is a highly selective calcium channel and a major route of calcium entry into mitochondria. How the channel catalyses ion permeation and achieves ion… (More)

Structural insight into the recognition of acetylated histone H3K56ac mediated by the bromodomain of CREB-binding protein.

• Li Xu, Aimin Cheng, +11 authors Ke Ruan
• The FEBS journal
• 2017

The acetylation of lysine 56 of histone H3 (H3K56ac) enhances the binding affinity of histone chaperones to H3-H4 dimers. CREB-binding protein (CBP) possesses a bromodomain that recognizes H3K56… (More)

Structural insights into the methyl donor recognition model of a novel membrane-binding protein UbiG

• Yuwei Zhu, Xuguang Jiang, +6 authors Xin Li
• Scientific reports
• 2016

UbiG is a SAM-dependent O-methyltransferase, catalyzing two O-methyl transfer steps for ubiquinone biosynthesis in Escherichia coli. UbiG possesses a unique sequence insertion between β4 and α10,… (More)

Structural basis for the specific recognition of 18S rRNA by APUM23

• Hongyu Bao, Na Wang, +5 authors Yunyu Shi
• Nucleic acids research
• 2017

PUF (Pumilio/fem-3 mRNA binding factor) proteins, a conserved family of RNA-binding proteins, recognize specific single-strand RNA targets in a specific modular way. Although plants have a greater… (More)

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