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18F-FDG PET predicts pathological response to preoperative chemoradiotherapy in patients with primary rectal cancer: a meta-analysis
TLDR
18F-FDG PET could be a potentially powerful non-invasive tool for predicting pathological response; the related parameters RI and SUVmax-post may be more suitable for the prediction of TRG than pCR. Expand
Fluorine-18 fluorodeoxyglucose positron emission tomography-computed tomography in monitoring the response of breast cancer to neoadjuvant chemotherapy: a meta-analysis.
TLDR
Analysis of the findings suggests that FDG-PET has moderately high sensitivity and specificity in early detection of responders from nonresponders, and can be applied in the evaluation of breast cancer response to neoadjuvant chemotherapy in patients with breast cancer. Expand
99mTc-labeled estradiol as an estrogen receptor probe: Preparation and preclinical evaluation.
TLDR
A new ER- binding probe, (99m)Tc-labeled estradiol, with diethylenetriaminepentaacetic acid (DTPA) as a chelating ligand was developed, and its targeting ability in vitro and in vivo was assessed, suggesting that Tc-DTPA-estradiol specifically targets ERs in tumors. Expand
Comparison of Whole-Body DWI and 18F-FDG PET/CT for Detecting Intramedullary and Extramedullary Lesions in Multiple Myeloma.
TLDR
For detecting intramedullary lesions, WB DWI is more sensitive than PET/CT in all regions except the skull, both in patients with a new diagnosis of multiple myeloma and in previously treated patients and especially in Patients with a low percentage of plasma cells. Expand
Imaging malignant melanoma with 18F-5-FPN
TLDR
18F-5-FPN specifically targeted melanin in vitro and in vivo with high retention and affinity and favourable pharmacokinetics and may be an ideal molecular probe for melanoma diagnosis and staging. Expand
A novel multivalent (99m)Tc-labeled EG2-C4bpα antibody for targeting the epidermal growth factor receptor in tumor xenografts.
TLDR
Tc-EG2-C4bpα specifically and efficiently targets EGFR over-expressing tumors suggesting that EG2- C4BPα may be a promising antibody alternative for future diagnostic application and potential radioimmunotherapy. Expand
TYR as a multifunctional reporter gene regulated by the Tet-on system for multimodality imaging: an in vitro study
TLDR
Results show that TYR induction of melanin production is regulated by the Tet-on system, and TYR-containing indicator cells may have utility in multimodality imaging. Expand
99mTc-labeled single-domain antibody EG2 in targeting epidermal growth factor receptor: an in-vitro and mouse model in-vivo study
TLDR
It is demonstrated that sdAb EG2 can effectively target EGFR in vitro and in vivo in tumors, suggesting that it could be used as a molecular probe for EGFR detection. Expand
Predictive value of 18F‐FDG PET/CT scanning in combination with clinical parameters in patients with newly diagnosed multiple myeloma
To evaluate the association of 18F‐2′‐deoxy 2′‐fluorodeoxyglucose (18F‐FDG) PET/CT with clinical parameters in predicting patients with newly diagnosed multiple myeloma (MM).
A novel technique for the preparation of 125I-5-trimethylstannyl-1-(2-deoxy-2-fluoro-beta-D-arabino-furanosyl) urail and its biodistribution pattern in Kunming mice
TLDR
The new method of radioiodinization of FTAU for the preparation of 125I-FIAU is easy, highly effective and stable in vivo and can serve as an imaging probe for myocardial reporter genes. Expand
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