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Mice devoid of glial fibrillary acidic protein (GFAP), an intermediate filament protein specifically expressed in astrocytes, develop normally and do not show any detectable abnormalities in the anatomy of the brain. In the cerebellum, excitatory synaptic transmission from parallel fibers (PFs) or climbing fibers (CFs) to Purkinje cells is unaltered, and(More)
The tuberous sclerosis complex (TSC)-mammalian target of rapamycin (mTOR) pathway is a key regulator of cellular metabolism. We used conditional deletion of Tsc1 to address how quiescence is associated with the function of hematopoietic stem cells (HSCs). We demonstrate that Tsc1 deletion in the HSCs drives them from quiescence into rapid cycling, with(More)
It is generally believed that a smooth execution of a compound movement, or motor coordination, requires learning of component movements as well as experience-based refinement of the motor program as a whole. PKC gamma mutant mice display impaired motor coordination but intact eyeblink conditioning, a form of component movement learning. Cerebellar(More)
Aggregate nearest neighbor query, which returns a common interesting point that minimizes the aggregate distance for a given query point set, is one of the most important operations in spatial databases and their application domains. This paper addresses the problem of finding the aggregate nearest neighbor for a merged set that consists of the given query(More)
Particle filters have been introduced as a powerful tool to estimate the posterior density of nonlinear systems. These filters are also capable of processing data online as required in many practical applications. In this paper, we propose a novel technique for video stabilization based on the particle filtering framework. Scale-invariant feature points are(More)
We describe Pantheia, a system that constructs virtual models of real spaces from collections of images, through the use of visual markers that guide and constrain model construction. To create a model users simply 'mark up' the real world scene by placing preprinted markers that describe scene elements or impose semantic constraints. Users then collect(More)
We improve the conversion efficiency of Ag2S quantum dot (QD)-sensitized TiO2 nanotube-array electrodes by chemically depositing ZnO recombination barrier layer on plain TiO2 nanotube-array electrodes. The optical properties, structural properties, compositional analysis, and photoelectrochemistry properties of prepared electrodes have been investigated. It(More)