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Prostaglandin E2 has no effect on two components of tetrodotoxin-resistant Na+ current in mouse dorsal root ganglion.
One possible mechanism underlying inflammation-induced sensitization of the primary afferent neuron is the upregulation of tetrodotoxin-resistant (TTX-R) Na(+) current by inflammatory mediators suchExpand
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Multiple types of Na+ currents mediate action potential electrogenesis in small neurons of mouse dorsal root ganglia
Small (<25 μm in diameter) neurons of the dorsal root ganglion (DRG) express multiple voltage-gated Na+ channel subtypes, two of which being resistant to tetrodotoxin (TTX). Each subtype mediates Na+Expand
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Functional roles of voltage-gated Na+ channels for pain sensation in different subpopulations of small dorsal root ganglion neurons
s / Neuroscience Research 58S (2007) S1–S244 S187 P3-a0 7 PSD-95 modulates the sensitivity of NR1/NR2A subtype NMDA receptor channels for a NMDA receptor antagonist, MK801 Yasue Yamada, Makoto InuiExpand
Does prostaglandin upregulate the tetrodotoxin-resistant Na+ current in DRG neurons?
Summary One possible mechanism underlying the inflammation-induced sensitization of primary afferent neurons is the upregulation of tetrodotoxin-resistant (TTX-R) Na + current by inflammatoryExpand