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OBJECT Sonic hedgehog (Shh) is a glycoprotein molecule that upregulates the transcription factor Gli1. The Shh protein plays a critical role in the proliferation of endogenous neural precursor cells when directly injected into the spinal cord after a spinal cord injury in adult rodents. Small-molecule agonists of the hedgehog (Hh) pathway were used in an(More)
Future processor chips will not be limited by the transistor resources, but will be mainly constrained by energy efficiency. Reconfigurable fabrics bring higher energy efficiency than CPUs via customized hardware that adapts to user applications. Among different reconfigurable fabrics, coarse-grained reconfigurable arrays (CGRAs) can be even more efficient(More)
As the gap between processor speed and memory speed continues to increase, memory system becomes the bottleneck of the processor. Multiple instructions queuing for accessing main memory appear frequently, the regular changes of the access address stream often appear as well. Utilizing the characteristics of memory access, and considering different speeds of(More)
As the gap between processor speed and memory speed continues to increase, memory system becomes the performance bottleneck of the processor. The memory system of stream architecture is different to that of general architecture, how to speed up the stream data access is a challenging issue for current stream architectures. This paper proposes a new memory(More)
BACKGROUND To study the expression of D2R, MGMT and VEGF for clinical significance in pituitary adenomas, and to predict the potential curative medical therapy of dopamine agonists, temozolomide and bevacizumab on pituitary adenomas. METHODS Immunohistochemistry and western blot were performed to detect the expression of expression of D2R, MGMT and VEGF(More)
The aim of the present study was to determine whether tumor necrosis factor (TNF)-α regulates the expression levels of excitatory amino-acid transporters (EAATs) in primary astrocytes and its roles in brain ischemia. Exogenous TNF-α was administered to pure cultured astrocytes and the expression levels of EAAT1, EAAT2 and glial fibrillary acidic protein(More)
This paper proposes a new type of processor architecture using a new program driving method which makes it possible for more programs to run in a single kernel processor concurrently without using interrupt technique. The main idea of the method is to collect all the program/instruction driving elements/factors to form a driving vector, called Program(More)
OBJECTIVE This study aims to evaluate whether the serum Anterior Gradient-2 (AGR2) can be used as a potential biomarker screening in the diagnosis of Pituitary adenomas(PAs). PATIENTS AND METHODS The serum AGR2 protein levels were preoperatively measured in 163 PA patients, 43 patients with other sellar lesions excluding PAs, 7 patients with prostate(More)
BACKGROUND Over the past several decades, the endoscopic endonasal transsphenoidal approach (EETA) has gradually become a preferred option of pituitary adenomas surgery because of its minimal invasiveness and high efficiency. However, some EETA operations were performed through one nostril (mononostril), while other EETA operations were performed through(More)