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OBJECT Sonic hedgehog (Shh) is a glycoprotein molecule that upregulates the transcription factor Gli1. The Shh protein plays a critical role in the proliferation of endogenous neural precursor cells when directly injected into the spinal cord after a spinal cord injury in adult rodents. Small-molecule agonists of the hedgehog (Hh) pathway were used in an(More)
Future processor chips will not be limited by the transistor resources, but will be mainly constrained by energy efficiency. Reconfigurable fabrics bring higher energy efficiency than CPUs via customized hardware that adapts to user applications. Among different reconfigurable fabrics, coarse-grained reconfigurable arrays (CGRAs) can be even more efficient(More)
As the gap between processor speed and memory speed continues to increase, memory system becomes the bottleneck of the processor. Multiple instructions queuing for accessing main memory appear frequently, the regular changes of the access address stream often appear as well. Utilizing the characteristics of memory access, and considering different speeds of(More)
BACKGROUND To study the expression of D2R, MGMT and VEGF for clinical significance in pituitary adenomas, and to predict the potential curative medical therapy of dopamine agonists, temozolomide and bevacizumab on pituitary adenomas. METHODS Immunohistochemistry and western blot were performed to detect the expression of expression of D2R, MGMT and VEGF(More)
OBJECTIVE: To study the effect of hyperventilat ion on brain tissue oxygen pressure (P(ti)O(2)), brain tissue carbon dio xide pressure (P(ti)O(2)), pH value and intracranial pressure (ICP) dur ing intracranial hypertension in pigs. METHODS: Autologous arterial blood (5.5 mlplus minus0.5 ml) was injected into the left frontal lobe by micropump to establish(More)
The clinical outcomes of transtibial (TT) and anteromedial (AM) drilling techniques for anterior cruciate ligament reconstruction in preparing the femoral tunnel were directly compared by using a systematic literature review. PubMed, EMBASE, the Cochrane Library, and the ISI Web of Science were searched until 10 May 2014, using the following Boolean(More)
BACKGROUND Over the past several decades, the endoscopic endonasal transsphenoidal approach (EETA) has gradually become a preferred option of pituitary adenomas surgery because of its minimal invasiveness and high efficiency. However, some EETA operations were performed through one nostril (mononostril), while other EETA operations were performed through(More)
PURPOSE Review the current evidence-based status of pulsed radiofrequency (PRF) treatment for patients with shoulder pain based on randomized controlled trials (RCTs) to provide a comprehensive analysis and a balanced view of the strengths and weaknesses of this treatment. METHODS PubMed, EMBASE, the Cochrane Library, and ISI Web of Science were searched(More)