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PURPOSE To measure by ultralong scan depth optical coherence tomography (UL-OCT) dimensional changes in the anterior segment of human eyes during accommodation. DESIGN Evaluation of diagnostic test or technology. PARTICIPANTS Forty-one right eyes of healthy subjects with a mean age of 34 years (range, 22-41 years) and a mean refraction of -2.5 ± 2.6(More)
OBJECTIVES The aim of this study was to determine the pattern of variations in tear osmolarity and tear meniscus volume in patients with dry eyes and in healthy control subjects over an 8-hr daytime period. METHODS Ten normal subjects (5 men and 5 women with a mean age of 27±7 years) and 10 dry eye patients (4 men and 6 women with a mean age of 36±12(More)
PURPOSE To measure vertical and horizontal thickness profiles of the central and peripheral corneal epithelium and determine if daytime changes occur. METHODS Forty eyes of 20 normal subjects were imaged by ultrahigh resolution spectral domain optical coherence tomography to profile the corneal epithelial thickness from the edge of Bowman layer to the(More)
Developments in optical coherence tomography (OCT) have expanded its clinical applications for ultra-high resolution imaging of the anterior segment of the human eye. This review presents the latest advances for imaging the anterior segment of the eye using ultra-high resolution OCT (UHR-OCT). Unique applications of UHR-OCT technology in clinical and basic(More)
PURPOSE To compare the ocular trauma score (OTS) and the paediatric penetrating ocular trauma score (POTS) as prognostic model for visual outcome in paediatric traumatic cataract cases after penetrating eye injuries. METHODS All children younger than 16 years with unilateral traumatic cataract following penetrating trauma between 2007 and 2012 were(More)
We report on a phase-based method for accurately measuring the ocular pulse in the anterior chamber in vivo. Using phase-sensitive optical coherence tomography with optimized scanning protocols and equations for compensating bulk motion and environmental vibrations, a high sensitivity of 0.9 μm/s minimal velocity is demonstrated at a wide detection band of(More)
PURPOSE To investigate changes in anterior chamber depth (ACD) and the distance between the Visian implantable Collamer lens (ICL) and the crystalline lens during pharmacologic accommodation in high myopia. DESIGN Prospective, comparative case series. PARTICIPANTS Thirty-three phakic eyes of 18 high myopic patients (range, -8.63 to -23.86 diopters) with(More)
The purpose of this study was to investigate the clinical characteristic and visual outcome of siderosis bulbi with retained intraocular foreign body (IOFB) and to validate the predictive value of the Ocular Trauma Score (OTS) in siderosis bulbi. Certain numerical values rendered to the OTS variables at present were summated (Table 1) and converted into 5(More)
NaCl based solutions were applied as osmotic stress agents to alter the hydration state of the mouse eye. Full-eye responses to these osmotic challenges were monitored in vivo using a custom-built optical coherence tomography (OCT) with an extended imaging range of 12.38 mm. Dynamic changes in the mouse eye were quantified based on the OCT images using(More)
PURPOSE To compare the preoperative characteristics of LASIK patients undergoing surgery in 1997 versus 2004 at one of the principal eye surgical centers in China. METHODS Preoperative data of patients who underwent LASIK in 1997 and 2004 were recorded and retrospectively compared. RESULTS In 1997, the mean spherical equivalent refraction of the 824(More)