Chiu Bin Hsiao

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BACKGROUND Nosocomial outbreaks of tuberculosis (TB) have been attributed to unrecognized pulmonary TB. Accurate assessment in identifying index cases of active TB is essential in preventing transmission of the disease. OBJECTIVES To develop an artificial neural network using clinical and radiographic information to predict active pulmonary TB at the time(More)
We report that cocaine may act as cofactor in HIV pathogenesis by increasing dendritic cell-specific C type ICAM-3-grabbing nonintegrin (DC-SIGN) expression on dendritic cells (DC). Our results show that cocaine-using, long-term nonprogressors and normal progressors of HIV infection manifest significantly higher levels of DC-SIGN compared with(More)
We used proteomic analyses to assess how drug abuse modulates immunologic responses to infections with the human immunodeficiency virus type 1 (HIV-1). Two-dimensional difference gel electrophoresis was utilized to determine changes in the proteome of peripheral blood mononuclear cells (PBMC) isolated from HIV-1-positive donors that occurred after treatment(More)
In the field of biomedicine, it is becoming increasingly apparent that a huge amount of genomic and clinical data are being generated everyday. Although these data, stored in different formats at multiple sources, help us acquire more information about the patients, the scale and complexity of these datasets result in the challenges of integration of(More)
We report a linezolid-resistant Enterococcus faecalis infection in a cord blood stem cell transplant recipient previously treated with linezolid for bloodstream infections by vancomycin-resistant enterococci. Sequencing showed a G2576U mutation in the 23S rRNA gene. Because of the important niche of linezolid in cancer treatment, linezolid-resistant E.(More)
Transmitted drug resistance (TDR) is an ongoing public health problem in HIV disease treatment and increases the risk of virologic failure following combination anti-retroviral therapy (cART) initiation. Current HIV treatment guidelines recommend resistance testing at entry into HIV care and at cART initiation. In this study, we longitudinally observed 10(More)
OBJECTIVE To evaluate the ability of once daily reduced dose clarithromycin to prevent disseminated Mycobacterium avium complex (dMAC) infection in patients with advanced HIV disease. DESIGN Non-randomized, retrospective study. SETTING Outpatient clinic of an urban university-affiliated municipal hospital. PATIENTS A group of 192 HIV-infected patients(More)
Isoenzyme profiles were obtained following polyacrylamide gel electrophoresis of crude extracts of Candida albicans and C. tropicalis. The two species were separated by distinct isoenzyme patterns. Within each species, variations were found for several isoenzymes. This allowed the development of a method for biotyping these fungi. Isoenzyme patterns of the(More)
Co-training has been proved successful in classifying many different kinds of data, such as text data and web data, which have naturally split views. Using these views as feature sets respectively, classifiers could make less generalization errors by maximizing their agreement over the unlabeled data. However, this method has limited performance in gene(More)
Branhamella catarrhalis causes lower respiratory tract infections in patients with chronic obstructive pulmonary disease. The outer membrane protein CD (OMP-CD) of B. catarrhalis is a major, heat-modifiable OMP. The goals of this study are to characterize the degree of conservation of OMP-CD among strains and to investigate if OMP-CD maintains its(More)