Chisato Fujimoto

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Loud air-conducted sound or bone-conducted vibration produces vestibular-dependent electromyographic responses both in the cervical muscles (cervical vestibular evoked myogenic potentials) and in the extraocular muscles (ocular vestibular evoked myogenic potentials; oVEMPs). Although previous frequency tuning measurements of cervical vestibular evoked(More)
Age-related hearing loss (ARHL), the progressive loss of hearing associated with aging, is the most common sensory disorder in the elderly population. The pathology of ARHL includes the hair cells of the organ of Corti, stria vascularis, and afferent spiral ganglion neurons as well as the central auditory pathways. Many studies have suggested that the(More)
CONCLUSION Ocular vestibular evoked myogenic potentials (oVEMPs) to binaural air-conducted stimulation (ACS) may provide a convenient way of assessing the crossed vestibulo-ocular reflex in patients with vestibular dysfunction as well as in healthy subjects. OBJECTIVE To investigate the clinical feasibility of using oVEMPs in response to binaural ACS to(More)
In this study, we established a novel enhanced green fluorescent protein (EGFP) reporter mouse line that enables the visualization of the placode-derived inner ear sensory cell lineage. EGFP was initially expressed in the otic placode and throughout its differentiation process into the inner ear sensory patches. At embryonic day 10.5 (E10.5), EGFP was(More)
OBJECTIVE To clarify the origin and pathways of ocular vestibular evoked myogenic potentials (oVEMPs) to air-conducted sound (ACS), we compared the results of oVEMPs with ACS, with oVEMPs with bone-conducted vibration (BCV), cervical VEMPs (cVEMPs) with ACS, and the caloric test in patients with unilateral vestibular schwannoma (VS). STUDY DESIGN(More)
OBJECTIVE This study examined the diagnostic value of the vestibular-evoked myogenic potential (VEMP) in comparison with the caloric test in patients with vestibular schwannoma (VS). METHODS Data were retrospectively collected from 803 consecutive patients who visited our vertigo clinic and underwent vestibular tests. Amongst them, 78 patients were(More)
OBJECTIVES Simple tests to detect peripheral vestibulopathy might be practically useful before conducting elaborate examinations. The purpose of this study was to assess the diagnostic accuracy of foam posturography for peripheral vestibulopathy, with emphasis on visual and somatosensory dependence. METHODS Two-legged stance tasks were conducted in(More)
OBJECTIVES We report, with neuro-otologic findings, a very rare case of a large jugular bulb diverticulum eroding the internal auditory canal (IAC). METHODS We present the imaging and functional studies of a 29-year-old woman in whom a large jugular bulb diverticulum on the left side was found incidentally. RESULTS Imaging studies revealed a normal(More)
OBJECTIVES Cervical vestibular evoked myogenic potentials (cVEMPs) have been found to be useful for clinical testing of vestibular function. Recently, investigators showed that short-latency, initially negative surface EMG potentials can be recorded around the extraocular muscles (oVEMPs) in response to air-conducted sound (ACS), bone-conducted vibration(More)
The primary afferent neurons of the vestibular ganglion convey sensory information from hair cells in the semicircular canals and otolith organs to the vestibular nuclei, the adjacent brainstem and the cerebellum. The intrinsic firing properties of vestibular ganglion cells (VGCs) are heterogeneous and have been classified into phasic, intermediate and(More)